| Charles Inge | | |
| William Ralph Inge | Dean of St Pauls | 1860–1954 |
| Jean Ingelow | British writer | 1820–1897 |
| Robert G. Ingersoll | Union United States Army offi… | 1833–1899 |
| Bernard Ingham | British journalist | 1932 |
| Bob Inglis | Former U.S. congressman | 1959 |
| Tsai Ing-wen | President of the Republic of … | 1956 |
| James Inhofe | American politician | 1934 |
| Paul Tschang In-Nam | korean prelate of the Catholi… | 1949 |
| Neil Innes | British comic songwriter | 1944–2019 |
| Harold Innis | Canadian professor of politic… | 1894–1952 |
| Takehiko Inoue | Japanese artist | 1967 |
| Daniel Inouye | American politician from Hawa… | 1924–2012 |
| Emilio Insolera | Actor and film producer | 1979 |
| Massimo Introvigne | Italian philosopher | 1955 |
| Inzamam-ul-Haq | | |
| Eugéne Ionesco | Romanian playwright | 1909–1994 |
| Jimmy Iovine | American music executive | 1953 |
| Ippen | Japanese Buddhist monk, found… | 1239–1289 |
| Eric Roll, Baron Roll of Ipsden | British economist | 1907–2005 |
| Muhammad Iqbál | Urdu poet and leader of the P… | 1877–1938 |
| Anosh Irani | Canadian writer | 1974 |
| Smriti Irani | Indian politician | 1972 |
| Faisal I of Iraq | King of Syria | 1883–1933 |
| James Iredell | one of the first Justices of … | 1751–1799 |
| Kathy Ireland | American model and businesswo… | 1963 |
| Irenaeus | Bishop and saint | 130–202 |
| Markéta Irglová | Czech singer-songwriter, musi… | 1988 |
| Manuel Fraga Iribarne | Spanish politician | 1922–2012 |
| Luce Irigaray | feminist, philosopher, lingui… | 1930 |
| Josu Iriondo | Catholic bishop | 1938 |
| Jeremy Irons | English actor | 1948 |
| Ernie Irvan | American racing driver | 1959 |
| David Irving | British writer and Holocaust … | 1938 |
| John Irving | American novelist and screenw… | 1942 |
| Kyrie Irving | American basketball player | 1992 |
| Washington Irving | writer, historian and diploma… | 1783–1859 |
| James Irwin | American astronaut | 1930–1991 |
| Robert Irwin | American artist | 1928 |
| Steve Irwin | Australian environmentalist a… | 1962–2006 |
| Jeremy Isaacs | British opera manager | 1932 |
| Walter Isaacson | American writer and biographer | 1952 |
| Judas Iscariot | one of the twelve original ap… | |
| Nancy Isenberg | American historian | 1958 |
| Ibn Ishaq | Arab historian | 704–767 |
| Christopher Isherwood | English novelist | 1904–1986 |
| Kazuo Ishiguro | Japanese-born British author | 1954 |
| Satomi Ishihara | Japanese actress | 1986 |
| Kaoru Ishikawa | Japanese business theorist | 1915–1989 |
| Takuboku Ishikawa | Japanese writer | 1886–1912 |
| Ishme-Dagan | King of Isin | |
| Kazi Nazrul Islam | Bengali poet | 1899–1976 |
| Yakoub Islam | | |
| Heinz Isler | engineer | 1926–2009 |
| Moulay Ismail | second ruler of the Moroccan … | 1646–1727 |
| Wan Azizah Wan Ismail | Malaysian politician | 1952 |
| Hastings Ismay | Army officer | 1887–1965 |
| Isocrates | ancient greek rhetorician | -436–-338 BC |
| Isidore Isou | Romanian-born French poet, fi… | 1925–2007 |
| Jozef Israëls | Dutch painter | 1824–1911 |
| Moses Isserles | Polish rabbi | 1520–1572 |
| Alec Issigonis | British car designer | 1906–1988 |
| Otmar Issing | German economist | 1936 |
| Seishirō Itagaki | Japanese general | 1885–1948 |
| Tomonobu Itagaki | Japanese video game designer | 1967 |
| Silius Italicus | Roman consul, orator, and Lat… | 26–101 |
| Nelson Itodo | Nigerian Entrepreneur | 2001 |
| Elizabeth Itotia | Kenyan nuclear pharmacist (bo… | 1992 |
| Aga Khan IV | 49th and current Imam of Niza… | 1936 |
| Agis IV | King of Sparta | -265–-241 BC |
| George S. Patton IV | U.S. Army general | 1923–2004 |
| Krishna Raja Wadiyar IV | King of Mysore | 1884–1940 |
| Timothy Dwight IV | American historian | 1752–1817 |
| Bidzina Ivanishvili | Georgian businessman and expr… | 1956 |
| Gjorge Ivanov | President of Macedonia | 1960 |
| Vasyl Ivasyuk | | 1960 |
| Jonathan Ive | English designer and VP of De… | 1967 |
| Allen Iverson | American basketball player | 1975 |
| Kenneth E. Iverson | Canadian computer scientist | 1920–2004 |
| Charles Ives | American composer | 1874–1954 |
| Molly Ivins | American journalist | 1944–2007 |
| Alexandra Ivy | American novelist | 1961 |
| Mineko Iwasaki | Japanese Geisha | 1949 |
| Satoru Iwata | Japanese video game programme… | 1959–2015 |
| Pope Pius IX | 255th Pope of the Catholic Ch… | 1792–1878 |
| B.K.S. Iyengar | Indian yoga teacher and schol… | 1918–2014 |
| Masti Venkatesha Iyengar | Indian writer | 1891–1986 |
| Divya S. Iyer | Indian bureaucrat | 1984 |
| Pico Iyer | British writer | 1957 |
| Alija Izetbegović | Chairman of the Presidency of… | 1925–2003 |
| Iburi Izō | | 1833–1907 |
| Eddie Izzard | British stand-up comedian, ac… | 1962 |
