| Malcolm X | American human rights activist | 1925–1965 |
| Pope Leo X | Pope from 1513 to 1521 | 1475–1521 |
| Pope Pius X | Catholic Pope and saint | 1835–1914 |
| Francis Xavier | Navarrese Basque Roman Cathol… | 1506–1552 |
| Iannis Xenakis | Greek composer | 1922–2001 |
| Xenophanes | Presocratic philosopher | -570–-475 BC |
| Xenophon | ancient Greek historian and p… | -430–-354 BC |
| Nick Xenophon | Australian politician | 1959 |
| Cai Xia | Chinese political scientist | 1952 |
| Zhou Xianwang | Chinese politician | 1963 |
| Tang Xianzu | Chinese playwright | 1550–1616 |
| Liu Xiaobo | Chinese literary critic, writ… | 1955–2017 |
| Deng Xiaoping | Chinese politician, Paramount… | 1904–1997 |
| Ma Xiaowei | Chinese politician | 1959 |
| Jenny Xie | American poet | |
| Pope Pius XII | 260th Pope of the Catholic Ch… | 1876–1958 |
| Pope Leo XIII | 256th Pope of the Catholic Ch… | 1810–1903 |
| Hu Xijin | Chinese journalist | 1960 |
| Bo Xilai | former Politburo member of th… | 1949 |
| Bing Xin | Chinese writer | 1900–1999 |
| Jin Xing | | |
| Gao Xingjian | Chinese novelist and playwrig… | 1940 |
| Huangbo Xiyun | Chinese Zen Buddhist | |
| Xuanzang | Chinese Buddhists monk, schol… | 602–664 |
| Cao Xueqin | Chinese writer during the Qin… | 1724–1763 |
| Qian Xuesen | Chinese rocket scientist | 1911–2009 |
| Lu Xun | Chinese novelist and essayist | 1881–1936 |
| He Xuntian | Chinese musician | 1953 |
| Trần Tế Xương | poet | 1870–1907 |
| Pope Benedict XV | 258th Pope of the Catholic Ch… | 1854–1922 |
| Pope Benedict XVI | 265th Pope of the Catholic Ch… | 1927 |
| Pope John XXIII | 261st Pope of the Catholic Ch… | 1881–1963 |
