| Rishi Sunak | Chancellor of the Exchequer o… | 1980 |
| Adrianus Sunarko | Indonesian Roman Catholic bis… | 1966 |
| Billy Sunday | American evangelist and baseb… | 1862–1935 |
| Peter Sunde | Swedish activist and computer… | 1978 |
| Abby Sunderland | Camera Assistant, Inspiration… | 1993 |
| Pär Sundström | Swedish bassist | 1981 |
| Ts'ao Sung | | 830–901 |
| Tomislav Sunić | Croatian-American writer, tra… | 1953 |
| Bhaskar Sunkara | American writer | 1989 |
| John E. Sununu | American politician | 1964 |
| Patrick Suppes | philosopher from United State… | 1922–2014 |
| Kamala Surayya | Indian author | 1934–2009 |
| Al B. Sure! | American musician | 1968 |
| Sher Shah Suri | founder of Sur Empire in Nort… | 1486–1545 |
| Luciano Suriani | Vatican archbishop and diplom… | 1957 |
| James Surowiecki | American journalist | 1967 |
| Henry Howard, Earl of Surrey | English Earl | 1516–1547 |
| Robert Smith Surtees | English writer | 1805–1864 |
| Jacqueline Susann | Novelist, actress | 1918–1974 |
| Patrick Süskind | German writer and screenwriter | 1949 |
| Henry Suso | Dominican friar and mystic | 1295–1366 |
| Meghan, Duchess of Sussex | American former actress and m… | 1981 |
| Prince Harry, Duke of Sussex | a member of the British royal… | 1984 |
| Leonard Susskind | American physicist | 1940 |
| Rosemary Sutcliff | English author | 1920–1992 |
| George Sutherland | Associate Justice of the U.S.… | 1862–1942 |
| Graham Sutherland | English artist | 1903–1980 |
| Kiefer Sutherland | English-Canadian actor, direc… | 1966 |
| Graham Sutton | Welsh scientist | 1903–1977 |
| Alexander Suvorov | Russian military commander | 1730–1800 |
| Joseph Theodorus Suwatan | Indonesian Roman Catholic bis… | 1940 |
| Han Suyin | physician and author | 1917–2012 |
| Helen Suzman | South African politician | 1917–2009 |
| David Suzuki | Canadian popular scientist an… | 1936 |
| D.T. Suzuki | Japanese author and philosoph… | 1870–1966 |
| Ichiro Suzuki | Japanese baseball player | 1973 |
| Kōji Suzuki | Japanese writer | 1957 |
| Shunryu Suzuki | Japanese Buddhist missionary | 1904–1971 |
| Ksenia Svetlova | Israeli journalist | 1977 |
| Italo Svevo | Italian writer | 1861–1928 |
| Caridad Svich | American writer | 1963 |
| Jimmy Swaggart | pastor, musician, teacher, te… | 1935 |
| Paul J. Swain | Catholic bishop | 1943–2022 |
| Roger Swain | American television personali… | 1949 |
| Bhakti Tirtha Swami | American Hindu writer | 1950–2005 |
| Om Swami | Indian mystic | 1979 |
| Radhanath Swami | Gaudiya Vaishnava guru | 1950 |
| Ganapathy Sachchidananda Swamiji | Indian guru | 1942 |
| M. S. Swaminathan | Indian scientist | 1925 |
| Subramanian Swamy | Indian politician | 1939 |
| Bob Swan | American business executive | 1960 |
| Teal Swan | American spiritual teacher | 1984 |
| Cub Swanson | American mixed martial artist | 1983 |
| Gloria Swanson | American actress | 1899–1983 |
| Michael Swanwick | American science fiction auth… | 1950 |
| Sushma Swaraj | Indian politician | 1952–2019 |
| Aaron Swartz | computer programmer and inter… | 1986–2013 |
| John Swartzwelder | 1950; comedy writer and novel… | 1950 |
| Ram Swarup | Indian historian | 1920–1998 |
| Vikas Swarup | Indian novelist and diplomat | 1961 |
| Carl XVI Gustaf of Sweden | King of Sweden | 1946 |
| Emanuel Swedenborg | Swedish 18th century scientis… | 1688–1772 |
| Paul Sweeney | Scottish politician | 1989 |
| Victoria Sweet | Physician | |
| Skye Sweetnam | Canadian singer-songwriter | 1988 |
| Paul Sweezy | American economist | 1910–2004 |
| John Sweller | educational psychologist | 1946 |
| Sophie Swetchine | Russian salon-holder | 1782–1857 |
| Graham Swift | English writer | 1949 |
| Jonathan Swift | Anglo-Irish satirist, essayis… | 1667–1745 |
| Patrick Swift | British artist | 1927–1983 |
| Taylor Swift | American singer-songwriter | 1989 |
| Brian Swimme | American cosmologist | 1950 |
| Algernon Charles Swinburne | English poet, playwright, nov… | 1837–1909 |
| Jo Swinson | British politician and leader… | 1980 |
| Owen Swiny | Irish theatre manager | 1676–1754 |
| Barry Switzer | American football player and … | 1937 |
| Kathrine Switzer | American distance runner | 1947 |
| Anthony Swofford | American writer and United St… | 1970 |
| Eric Sykes | English actor and director | 1923–2012 |
| Oliver Sykes | British musician | 1986 |
| Plum Sykes | British fashion writer | 1969 |
| Buddy de Sylva | American musician | 1895–1950 |
| James Joseph Sylvester | English mathematician | 1814–1897 |
| Joshua Sylvester | English poet | 1563–1618 |
| Ronald Syme | New Zealand-born historian an… | 1903–1989 |
| Charles Symmons | Welsh poet | 1749–1826 |
| John Addington Symonds | English poet and literary cri… | 1840–1893 |
| Arthur Symons | British poet | 1865–1945 |
| Red Symons | Australian broadcaster and mu… | 1949 |
| John Millington Synge | Irish playwright, poet, prose… | 1871–1909 |
| Dionysius I of Syracuse | Sicilian tyrant | -430–-367 BC |
| Ephrem the Syrian | Syriac deacon and a prolific … | 306–373 |
| John Szarkowski | American curator | 1925–2007 |
| Thomas Szasz | Hungarian psychiatrist | 1920–2012 |
| Stefan Szczesny | German painter and sculptor | 1951 |
| Michael Szenberg | American economist | 1934 |
| Albert Szent-Györgyi | Hungarian biochemist who won … | 1893–1986 |
| Leó Szilárd | Physicist and biologist | 1898–1964 |
| Hsu Szu-chien | Taiwanese politician | |
