Sad and heartbreaking quotes
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[Andy Rooney, w:Andy Rooney, 6, Credits, Years of Minutes, 2003, PublicAffairs, 978-1586482114]

“The eternal quest of the individual human being is to shatter his loneliness.”
Human Options (1981)

Source: Debt: The First 5,000 Years (2011), Chapter Twelve, "1971–The Beginning…", p. 384

Open letter to Barrantes on the Noli, published in La Solidaridad (15 February 1890)

“If people would know how little brain is ruling the world, they would die of fear.”

“I am not, I will not be.
I have not, I will not have.”
That frightens all the childish
And extinguishes fear in the wise.
§ 26
Major attributed works, Ratnāvalī (Precious Garland)

“I like the saying "The world is as you are."”
The Circle, p. 21
Catching the Big Fish (2006)
Context: I like the saying "The world is as you are." And I think films are as you are. That's why, although the frames of a film are always the same — the same number, in the same sequence, with the same sounds — every screening is different. The difference is sometimes subtle but it's there. It depends on the audience. There is a circle that goes from the audience to the film and back. Each person is looking and thinking and feeling and coming up with his or her own sense of things. And it's probably different from what I fell in love with.
So you don’t know how it's going to hit people. But if you thought about how it's going to hit people, or if it's going to hurt someone, or if it's going to do this or do that, then you would have to stop making films. You just do these things that you fall in love with, and you never know what's going to happen.

“One word
Frees us of all the weight and pain of life:
That word is love.”
Source: Oedipus at Colonus, Line 1616–18

“To ease another's heartache is to forget one's own.”
Quoted in a Edith A. Sawyer (1899), Mary Cameron
Misattributed

Source: 1860s, Second State of the Union address (1862)

“Those who look for the bad in people will surely find it.”

Letter to Blumentritt (24 December 1886)

“Optimism doesn’t wait on facts. It deals with prospects. Pessimism is a waste of time.”
Human Options (1981)

Misattributed to Meryl Streep (and widely disseminated on the Internet as of August/September 2014), this quote is allegedly a translation of a text by the author José Micard Teixeira, the original of which begins (in Portuguese): "Já não tenho paciência para algumas coisas, não porque me tenha tornado arrogante..."
Misattributed

“You don't forget the face of the person who was your last hope.”
Katniss Everdeen, p. 85
Source: The Hunger Games trilogy, The Hunger Games (2008)