“Escape, God how we all need escape from this tiny here. The need for it has motivated just about everything man has ever done in any direction other than that of the satisfaction of his physical appetites; it has led him along weird and wonderful pathways; it has led him into art and religion, ascetism and astrology, dancing and drinking, poetry and insanity. All of these have been escapes because he has known only recently the true direction of escape—outward, into infinity and eternity, away from this little flat if rounded surface we’re born on and die on. This mote in the solar system, this atom in the galaxy.”

Speech at the National Press Club (2004)

Letter to J. Vernon Shea (7 August 1931), quoted in "H.P. Lovecraft, a Life" by S.T. Joshi, p. 579
Non-Fiction, Letters

Source: Midnight's Children

Source: Man for Himself (1947), Ch. 3 "Human Nature and Character

Source: Parable of the Talents

Chantal, p. 112
La joie (Joy) 1929

Wording in Ideas and Opinions: Everything that the human race has done and thought is concerned with the satisfaction of deeply felt needs and the assuagement of pain. One has to keep this constantly in mind if one wishes to understand spiritual movements and their development. Feeling and longing are the motive force behind all human endeavor and human creation, in however exalted a guise the latter may present themselves to us.
1930s, Religion and Science (1930)
Context: Everything that men do or think concerns the satisfaction of the needs they feel or the escape from pain. This must be kept in mind when we seek to understand spiritual or intellectual movements and the way in which they develop. For feelings and longings are the motive forces of all human striving and productivity—however nobly these latter may display themselves to us.

Neville Cardus in the Manchester Guardian, 1935; reprinted in his The Delights of Music (1966) p. 56.
Criticism