“A man who, beyond the age of 26, finds himself on a bus can count himself as a failure.”
Attributed to her in Commons debates, 2003-07-02, column 407 http://www.parliament.the-stationery-office.co.uk/pa/cm200203/cmhansrd/vo030702/debtext/30702-10.htm and Commons debates, 2004-06-15 column 697 http://www.publications.parliament.uk/pa/cm200304/cmhansrd/vo040615/debtext/40615-20.htm#40615-20_spnew1. According to a letter http://www.telegraph.co.uk/core/Content/displayPrintable.jhtml?xml=/opinion/2006/11/02/nosplit/dt0201.xml&site=15&page=0 to the Daily Telegraph by Alistair Cooke on 2 November 2006, this sentiment originated with Loelia Ponsonby, one of the wives of 2nd Duke of Westminster who said "Anybody seen in a bus over the age of 30 has been a failure in life". In a letter http://www.telegraph.co.uk/comment/letters/3633852/Letters-to-the-Daily-Telegraph.html published the next day, also in the Daily Telegraph, Hugo Vickers claims Loelia Ponsonby admitted to him that she had borrowed it from Brian Howard. There is no solid evidence that Margaret Thatcher ever quoted this statement with approval, or indeed shared the sentiment.
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Margaret Thatcher 348
British stateswoman and politician 1925–2013Related quotes

“But he who neither thinks for himself nor learns from others, is a failure as a man.”
Source: Works and Days and Theogony

“Who can know heaven except by its gifts? and who can find out God, unless the man who is himself an emanation from God?”
Quis cœlum possit nisi cœli munere nosse?
Et reperire deum nisi qui pars ipse deorum est?
Astronomica

Source: Défense des Lettres [In Defense of Letters] (1937), p. 42

“Man needs to go outside himself in order to find repose and reveal himself.”
"Vivir en Sí" [To Live in Oneself] (1891)

“The man who renounces himself, comes to himself.”
The Divinity College Address (1838) : full title “An Address Delivered Before the Senior Class in Divinity College, Cambridge, Sunday Evening, July 15, 1838”, given at Harvard Divinity School : as contained in The Spiritual Emerson: Essential Writings, Emerson, ed. David M Robinson, Beacon Press (2004), p. 78 : ISBN 0807077194

“Only a man who is at one with the world can be at one with himself.”
Nur wer einig ist mit der Welt kann einig seyn mit sich selbst.
“Ideas,” Lucinde and the Fragments, P. Firchow, trans. (1991), § 130