“Chemical reasoning, as used both in applications and in basic research, resembles a detective story in which tangible clues lead to a mental picture of events never directly witnessed by the detective.”

Principles of Modern Chemistry (7th ed., 2012), Ch. 1 : The Atom in Modern Chemistry

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David W. Oxtoby13

President of Pomona college 1951

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“Following the trail of events from some point in the past to a piece of modern technology is rather like a detective story, with you as the detective, knowing only as much as the people in the past do, and like them having to guess at what was likely to happen next.”

James Burke (science historian) (1936) British broadcaster, science historian, author, and television producer

Connections (1979), 1 - The Trigger Effect
Context: And that's why following the trail from the past up to the emergence of the modern technology that surrounds us in our daily lives, and affects our lives, is rather like a detective story. Because, at no time in the past, did anybody have anything to do with the business of inventing or changing things, ever know what the full effect of his actions would be. He just went ahead and did what he did for his own reasons, like we do. That's how change comes about. And it's like a detective story because if you follow the trail from the past up to a modern man-made object, the story is full of sudden twists and false clues and guesswork, and you never know where the story is heading until the very last minute.
Context: I would say it was a pretty safe bet, that the one magic wish most people would like to be granted would be to be able to see into the future. Think what it would mean. And backing the right horse! But we can't. We have to guess about tomorrow and we have to act on that guess, and it's never been any different. And that's why following the trail from the past up to the emergence of the modern technology that surrounds us in our daily lives, and affects our lives, is rather like a detective story. Because, at no time in the past, did anybody have anything to do with the business of inventing or changing things, ever know what the full effect of his actions would be. He just went ahead and did what he did for his own reasons, like we do. That's how change comes about. And it's like a detective story because if you follow the trail from the past up to a modern man-made object, the story is full of sudden twists and false clues and guesswork, and you never know where the story is heading until the very last minute.