“My quotations from Newton suggest the motive which induced him to take a stand against the use of hypotheses, namely, the danger of becoming involved in disagreeable controversies. …Newton could no more dispense with hypotheses in his own cogitations than an eagle can dispense with flight. Nor did Newton succeed in avoiding controversy.”
Explanatory Appendix, Sir Isaac Newton's Mathematical Principles of Natural Philosophy and His System of the World (1934) Tr. Andrew Motte, p. 674
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Florian Cajori 13
American mathematician 1859–1930Related quotes

“God can dispense with us just as little as we can dispense with him.”
Gott kann uns ebensowenig entbehren wie wir ihn.
Sermon 49
[Pavel Kroupa, Has dogma derailed the scientific search for dark matter?, aeon.co, November 2016, https://aeon.co/ideas/has-dogma-derailed-the-scientific-search-for-dark-matter]

Context: There is no reason why an extraphysical general principle is necessarily to be avoided, since such principles could conceivably serve as useful working hypotheses. For the history of scientific research is full of examples in which it was very fruitful indeed to assume that certain objects or elements might be real, long before any procedures were known which would permit them to be observed directly.

Part of an unsigned foreword to Copernicus' De revolutionibus orbium coelestium, actually written by Andreas Osiander.
Misattributed
[Calculus as an Experimental Science, 78, 6, 1971, 664–667, The American Mathematical Monthly, 10.2307/2316582]

"What Can I Do To Make Your Flight More Uncomfortable? (22 November 2006) http://www.anncoulter.com/cgi-local/printer_friendly.cgi?article=158
2006

Letter to Fatio de Duillier (11 July 1687), quoted in René Dugas, Mechanics in the seventeenth century (1958), p. 440