“Those distinct substances, which concretes generally either afford, or are made up of, may, without very much inconvenience, be called the elements or principles of them.”

Part I, Proposition IV
The Sceptical Chymist (1661)

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Robert Boyle 21
English natural philosopher, chemist, physicist, and invent… 1627–1691

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“There cannot be a single, simple body which is infinite, either, as some hold, one distinct from the elements, which they then derive from it, nor without this qualification.”

Anaximander (-610–-547 BC) pre-Socratic Greek philosopher

As quoted in Physics by Aristotle, as translated by John Burnet http://www.classicpersuasion.org/pw/burnet/egp.htm?pleaseget=14
Context: There cannot be a single, simple body which is infinite, either, as some hold, one distinct from the elements, which they then derive from it, nor without this qualification. For there are some who make this (i. e. a body distinct from the elements) the infinite, and not air or water, in order that the other things may not be destroyed by their infinity. They are in opposition one to another — air is cold, water moist, and fire hot—and therefore, if any one of them were infinite, the rest would have ceased to be by this time. Accordingly they say that what is infinite is something other than the elements, and from it the elements arise.

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“In the matter of reforming things, as distinct from deforming them, there is one plain and simple principle; a principle which will probably be called a paradox.”

G. K. Chesterton (1874–1936) English mystery novelist and Christian apologist

Source: The Thing (1929), Ch. IV : The Drift From Domesticity
Context: In the matter of reforming things, as distinct from deforming them, there is one plain and simple principle; a principle which will probably be called a paradox. There exists in such a case a certain institution or law; let us say, for the sake of simplicity, a fence or gate erected across a road. The more modern type of reformer goes gaily up to it and says, "I don't see the use of this; let us clear it away." To which the more intelligent type of reformer will do well to answer: "If you don't see the use of it, I certainly won't let you clear it away. Go away and think. Then, when you can come back and tell me that you do see the use of it, I may allow you to destroy it."
This paradox rests on the most elementary common sense. The gate or fence did not grow there. It was not set up by somnambulists who built it in their sleep. It is highly improbable that it was put there by escaped lunatics who were for some reason loose in the street. Some person had some reason for thinking it would be a good thing for somebody. And until we know what the reason was, we really cannot judge whether the reason was reasonable. It is extremely probable that we have overlooked some whole aspect of the question, if something set up by human beings like ourselves seems to be entirely meaningless and mysterious. There are reformers who get over this difficulty by assuming that all their fathers were fools; but if that be so, we can only say that folly appears to be a hereditary disease. But the truth is that nobody has any business to destroy a social institution until he has really seen it as an historical institution. If he knows how it arose, and what purposes it was supposed to serve, he may really be able to say that they were bad purposes, or that they have since become bad purposes, or that they are purposes which are no longer served. But if he simply stares at the thing as a senseless monstrosity that has somehow sprung up in his path, it is he and not the traditionalist who is suffering from an illusion.

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“I assume that cells, before their conversion into completely passive or "formed material," throw off minute granules or atoms, which circulate freely throughout the system, and when supplied with proper nutriment multiply by self-division, subsequently becoming developed into cells like those from which they were derived. These granules for the sake of distinctness may be called … gemmules. They are supposed to be transmitted from the parents to the offspring, and are generally developed in the generation which immediately succeeds, but are often transmitted in a dormant state during many generations and are then developed. Their development is supposed to depend on their union with other partially developed cells or gemmules which precede them in the regular course of growth. … Lastly, I assume that the gemmules in their dormant state have a mutual affinity for each other, leading to their aggregation either into buds or into the sexual elements. … These assumptions constitute the provisional hypothesis which I have called Pangenesis.”

volume II, chapter XXVII: "Provisional Hypothesis of Pangenesis", page 374 http://darwin-online.org.uk/content/frameset?pageseq=389&itemID=F877.2&viewtype=image
It is sometimes claimed that modern biologist are dogmatic "Darwinists" who uncritically accept all of Darwin's ideas. This is false: No one today accepts Darwin's hypothesis of gemmules and pangenesis.
The Variation of Animals and Plants under Domestication (1868)

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