The future of data analysis. Annals of Mathematical Statistics 33 (1), (1962), page 13.
Variant: "An approximate answer to the right question is worth a great deal more than a precise answer to the wrong question." "as the renowned statistician John Tukey once reportedly said," according to Super Freakonomics page 224.
“There are three great questions which in life we have over and over again to answer. Is it right or wrong? Is it true or false? Is it beautiful or ugly? Our education ought to help us to answer these questions.”
The Use of Life (1894), ch. VI: National Education
Source: The Use of Life http://archive.org/details/uselife02lubbgoog/page/n114/mode/2up on Archive.Org, pages 102—103
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John Lubbock, 1st Baron Avebury 7
British banker, Liberal politician, philanthropist, scienti… 1834–1913Related quotes

47 : The Question and its Answer, p. 78.
The Everything and the Nothing (1963)
Source: Philosophy in a New Key (1942), Ch. 1, p. 1

“If you don't ask the right question, every answer seems wrong”

Aristotle, 9.
The Lives and Opinions of Eminent Philosophers (c. 200 A.D.), Book 5: The Peripatetics

Autobiographical Essay (2001)
Source: Empiricism, Semantics, and Ontology (1950), Ch. 3. What does acceptance of a kind of entities mean?

As quoted in: Ṭhānissaro (Bhikkhu.) (2004) Handful of leaves. Vol. 3, p. 80
Anatol Rapoport, "Modern Systems Theory – An Outlook for Coping with Change", paper given in the 1970 John Umstead Distinguished Lectures at North Carolina Department of Mental Health, Research Division, on 5 February 1970, and appeared in Revue Francaise de Sociologie, October 1969, p. 16
1970s and later