“He that is highest and worthiest was most fully made-nought and most utterly despised.”
The Eighth Revelation, Chapter 20
Context: Thus I saw our Lord Jesus languoring long time. For the oneing with the Godhead gave strength to the manhood for love to suffer more than all men might suffer: I mean not only more pain than all men might suffer, but also that He suffered more pain than all men of salvation that ever were from the first beginning unto the last day might tell or fully think, having regard to the worthiness of the highest worshipful King and the shameful, despised, painful death. For He that is highest and worthiest was most fully made-nought and most utterly despised.
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Julian of Norwich 372
English theologian and anchoress 1342–1416Related quotes

As translated in A Dazzling Darkness: An Anthology of Western Mysticism (1985) by Patrick Grant
Context: The most powerful prayer, one wellnigh omnipotent, and the worthiest work of all is the outcome of a quiet mind. The quieter it is the more powerful, the worthier, the deeper, the more telling and more perfect the prayer is. To the quiet mind all things are possible. What is a quiet mind? A quiet mind is one which nothing weighs on, nothing worries, which, free from ties and from all self-seeking, is wholly merged into the will of God and dead to its own.

“Of all our infirmities, the most savage is to despise our being.”
Book III, Ch. 13
Attributed
Variant: Of all the infirmities we have, 'tis the most savage to despise our being. (Charles Cotton translation)

“She doeth little kindnesses
Which most leave undone, or despise.”
My Love. iv.
Bartlett's Familiar Quotations, 10th ed. (1919)
“Most of the things we need to be most fully alive never come in busyness. They grow in rest.”
Source: The Holy Wild: Trusting in the Character of God

Chè fortuna quaggiù varia a vicenda,
Mandandoci venture or triste, or buone:
A' voli troppo alti e repentini
Sogliono i precipizi esser vicini.
Canto II, stanza 70 (tr. Fairfax)
Gerusalemme Liberata (1581)

“All mankind, right down to those you most despise, are your neighbors.”
"Lost in Non-Translation" (1989), in Magic (Voyager, 1997) p. 270
General sources