What is Truth (1912)
“If we are not stupid or insincere when we say that the good or ill of man lies within his own will, and that all beside is nothing to us, why are we still troubled?”
Book I, ch. 25.
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Epictetus 175
philosopher from Ancient Greece 50–138Related quotes

The Wild Ass’s Skin (1831), Part II: A Woman Without a Heart
Context: A penniless man who has no ties to bind him is master of himself at any rate, but a luckless wretch who is in love no longer belongs to himself, and may not take his own life. Love makes us almost sacred in our own eyes; it is the life of another that we revere within us; then and so begins for us the cruelest trouble of all.

Attributed to Thoreau, in The Life You Were Born to Live : A Guide to Finding Your Life Purpose (1995) by Dan Millman, p. xi, and to Ralph Waldo Emerson in Promotion of Pharmaceuticals : Issues, Trends, Options (1993) by Dev S. Pathak, Alan Escovitz, and Suzan Kucukarslan, p. 74, but no occurrence of it prior to the 1990s has been located.
Disputed

Letter to Thomas Jefferson (17 January 1820). Often misquoted as "God is an essence that we know nothing of" and attached to a part of his 22 January 1825 letter to Thomas Jefferson.
1820s

Letter to Eugene Stoffels (Jan. 3, 1845) as quoted by Thomas Molnar, The Decline of the Intellectual (1961) Ch. 11 "Intellectual and Philosopher"
Original text:
Les hommes ne sont en général ni très-bons, ni très-mauvais : ils sont médiocres. [...] L'homme avec ses vices, ses faiblesses, ses vertus, ce mélange confus de bien et de mal, de bas et de haut, d'honnête et de dépravé, est encore, à tout prendre, l'objet le plus digne d'examen, d'intérêt, de pitié, d'attachement et d'admiration qui se trouve sur la terre; et puisque les anges nous manquent, nous ne saurions nous attacher à rien qui soit plus grand et plus digne de notre dévouement que nos semblables.
1840s

Pericles commenting the participation of Athenian citizens in politics, as quoted in Models of Democracy (2006) by David Held, Stanford University Press, p. 14. Book II, chapter 40.

“Montaigne,” p. 2
Reperusals and Recollections (1936)