“If I were granted omnipotence, and millions of years to experiment in, I should not think Man much to boast of as the final result of all my efforts.”

Colin Serjent, "Blake's 08, http://www.catalystmedia.org.uk/issues/nerve9/peter_blake.php Nerve, Autumn 2006
Life

Interview with The Guardian (February 1970)

Preface (1957)
1920s, Why I Am Not a Christian (1927)

On his years of research in developing the electric light bulb, as quoted in "Talks with Edison" by George Parsons Lathrop in Harper's magazine, Vol. 80 (February 1890), p. 425.
Context: During all those years of experimentation and research, I never once made a discovery. All my work was deductive, and the results I achieved were those of invention, pure and simple. I would construct a theory and work on its lines until I found it was untenable. Then it would be discarded at once and another theory evolved. This was the only possible way for me to work out the problem. … I speak without exaggeration when I say that I have constructed 3,000 different theories in connection with the electric light, each one of them reasonable and apparently likely to be true. Yet only in two cases did my experiments prove the truth of my theory. My chief difficulty was in constructing the carbon filament.... Every quarter of the globe was ransacked by my agents, and all sorts of the queerest materials used, until finally the shred of bamboo, now utilized by us, was settled upon.

Source: When Will Jesus Bring the Pork Chops?

Source: On the Steel Breeze (2013), Chapter 6 (p. 71)

Source: On Aggression (1963), Ch. XII : On the Virtue of Scientific Humility
Context: We are the highest achievement reached so far by the great constructors of evolution. We are their "latest" but certainly not their last word. The scientist must not regard anything as absolute, not even the laws of pure reason. He must remain aware of the great fact, discovered by Heraclitus, that nothing whatever really remains the same even for one moment, but that everything is perpetually changing. To regard man, the most ephemeral and rapidly evolving of all species, as the final and unsurpassable achievement of creation, especially at his present-day particularly dangerous and disagreeable stage of development, is certainly the most arrogant and dangerous of all untenable doctrines. If I thought of man as the final image of God, I should not know what to think of God. But when I consider that our ancestors, at a time fairly recent in relation to the earth's history, were perfectly ordinary apes, closely related to chimpanzees, I see a glimmer of hope. It does not require very great optimism to assume that from us human beings something better and higher may evolve. Far from seeing in man the irrevocable and unsurpassable image of God, I assert – more modestly and, I believe, in greater awe of the Creation and its infinite possibilities – that the long-sought missing link between animals and the really humane being is ourselves!

From a letter to H. P. Lovecraft (March 6, 1933)
Letters

George Brecht, 1957/58, cited in: George Brecht, ‎Alfred M. Fischer (2005). George Brecht: events : eine Heterospektive. p. 224