“No state of mind, not even positive suffering, is more painful than the want of interesting objects. The vacant soul preys on itself, and often rushes with impatience from the security which demands no effort, to the brink of peril.”

War (1816)
Context: One of the great springs of war may be found in a very strong and general propensity of human nature, in the love of excitement, of emotion, of strong interest; a propensity which gives a charm to those bold and hazardous enterprises which call forth all the energies of our nature. No state of mind, not even positive suffering, is more painful than the want of interesting objects. The vacant soul preys on itself, and often rushes with impatience from the security which demands no effort, to the brink of peril.

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William Ellery Channing 71
United States Unitarian clergyman 1780–1842

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“It is hopelessness even more than pain that crushes the soul.”

Source: Darkness Visible (1990), VI
Source: Darkness Visible: A Memoir of Madness
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In depression this faith in deliverance, in ultimate restoration, is absent. The pain is unrelenting, and what makes the condition intolerable is the foreknowledge that no remedy will come — not in a day, an hour, a month, or a minute. If there is mild relief, one knows that it is only temporary; more pain will follow. It is hopelessness even more than pain that crushes the soul. So the decision-making of daily life involves not, as in normal affairs, shifting from one annoying situation to another less annoying — or from discomfort to relative comfort, or from boredom to activity — but moving from pain to pain. One does not abandon, even briefly, one's bed of nails, but is attached to it wherever one goes.

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“In the matter of physics, the first lessons should contain nothing but what is experimental and interesting to see. A pretty experiment is in itself often more valuable than twenty formulae extracted from our minds.”

Albert Einstein (1879–1955) German-born physicist and founder of the theory of relativity

Conversations with Einstein by Alexander Moszkowski (1971), p. 69 http://books.google.com/books?id=_D3wAAAAIAAJ&q=%22first+lessons+should+contain+nothing+but+what%22#search_anchor. This is just Moszkowski's English translation of a statement he attributed to Einstein in his 1922 book Einstein, Einblicke in seine Gedankenwelt, p. 77 http://books.google.com/books?id=6zHPAAAAMAAJ&pg=PA77#v=onepage&q&f=false: "Was die Physik betrifft, fuhr Einstein fort, so darf für den ersten Unterricht gar nichts in Frage kommen, als das Experimentelle, anschaulich-Interessante. Ein hübsches Experiment ist schon an sich oft wertvoller, als zwanzig in der Gedankenretorte entwickelte Formeln." As Moszkowski makes clear in the original German text, this "quotation" is a paraphrasing of his conversation with Einstein.
Attributed in posthumous publications

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“The human mind is often, and I think it is for the most part, in a state neither of pain nor pleasure, which I call a state of indifference.”

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“To a man whose mind is free there is something even more intolerable in the sufferings of animals than in the sufferings of men.”

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Context: He could not think of the animals without shuddering in anguish. He looked into the eyes of the beasts and saw there a soul like his own, a soul which could not speak; but the eyes cried for it: "What have I done to you? Why do you hurt me?" He could not bear to see the most ordinary sights that he had seen hundreds of times—a calf crying in a wicker pen, with its big, protruding eyes, with their bluish whites and pink lids, and white lashes, its curly white tufts on its forehead, its purple snout, its knock-kneed legs:—a lamb being carried by a peasant with its four legs tied together, hanging head down, trying to hold its head up, moaning like a child, bleating and lolling its gray tongue:—fowls huddled together in a basket:—the distant squeals of a pig being bled to death:—a fish being cleaned on the kitchen-table.... The nameless tortures which men inflict on such innocent creatures made his heart ache. Grant animals a ray of reason, imagine what a frightful nightmare the world is to them: a dream of cold-blooded men, blind and deaf, cutting their throats, slitting them open, gutting them, cutting them into pieces, cooking them alive, sometimes laughing at them and their contortions as they writhe in agony. Is there anything more atrocious among the cannibals of Africa? To a man whose mind is free there is something even more intolerable in the sufferings of animals than in the sufferings of men. For with the latter it is at least admitted that suffering is evil and that the man who causes it is a criminal. But thousands of animals are uselessly butchered every day without a shadow of remorse. If any man were to refer to it, he would be thought ridiculous.—And that is the unpardonable crime. That alone is the justification of all that men may suffer.

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