“The progress of science is strewn, like an ancient desert trail, with the bleached skeletons of discarded theories which once seemed to possess eternal life.”

The Ghost in the Machine (1967, 1976).

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Arthur Koestler 25
Hungarian-British author and journalist 1905–1983

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“How do you know that the incessant progress of science will not compel scientists to consider that life has existed during eternity, and not matter?”

Louis Pasteur (1822–1895) French chemist and microbiologist

Partially quoted in René Dubos, Louis Pasteur: Free Lance of Science, Da Capo Press, Inc., 1950. p 396.
Original in French: «La génération spontanée, je la cherche sans la découvrir depuis vingt ans. Non, je ne la juge pas impossible. Mais quoi donc vous autorise à vouloir qu'elle ait été l'origine de la vie? Vous placez la matière avant la vie et vous faites la matière existante de toute éternité. Qui vous dit que, le progrès incessant de la science n'obligera pas les savants, qui vivront dans un siècle, dans mille ans, dans dix mille ans... à affirmer que la vie a été de toute éternité et non la matière.? Vous passez de la matière à la vie parce que votre intelligence actuelle, si bornée par rapport à ce que sera l'intelligence des naturalistes futurs, vous dit qu'elle ne peut comprendre autrement les choses. Qui m'assure que dans dix mille ans on ne considérera pas que c'est de la vie qu'on croira impossible de ne pas passer à la matière? Si vous voulez être au nombre des esprits scientifiques, s, qui seuls comptent, il faut vous débarrasser des idées et des raisonnements a priori et vous en tenir aux déductions nécessaires des faits établis et ne pas accorder plus de confiance qu'il ne faut aux déductions de pures hypothèses." (Pasteur et la philosophie,Patrice Pinet, Editions L'Harmattan, p. 63.
Context: I have been looking for spontaneous generation for twenty years without discovering it. No, I do not judge it impossible. But what allows you to make it the origin of life? You place matter before life and you decide that matter has existed for all eternity. How do you know that the incessant progress of science will not compel scientists to consider that life has existed during eternity, and not matter? You pass from matter to life because your intelligence of today cannot conceive things otherwise. How do you know that in ten thousand years, one will not consider it more likely that matter has emerged from life? You move from matter to life because your current intelligence, so limited compared to what will be the future intelligence of the naturalist, tells you that things cannot be understood otherwise. If you want to be among the scientific minds, what only counts is that you will have to get rid of a priori reasoning and ideas, and you will have to do necessary deductions not giving more confidence than we should to deductions from wild speculation.

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“May not the absolute and perfect eternal happiness be an eternal hope, which would die if it were realized? Is it possible to be happy without hope? And there is no place for hope once possession has been realized, for hope, desire, is killed by possession.”

Miguel de Unamuno (1864–1936) 19th-20th century Spanish writer and philosopher

The Tragic Sense of Life (1913), X : Religion, the Mythology of the Beyond and the Apocatastasis
Context: May not the absolute and perfect eternal happiness be an eternal hope, which would die if it were realized? Is it possible to be happy without hope? And there is no place for hope once possession has been realized, for hope, desire, is killed by possession. May it not be, I say, that all souls grow without ceasing, some in a greater measure than others, but all having to pass some time through the same degree of growth, whatever that degree may be, and yet without ever arriving at the infinite, at God, to whom they continually approach? Is not eternal happiness an eternal hope, with its eternal nucleus of sorrow in order that happiness shall not be swallowed up in nothingness?

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“The ancient bitter opposition to improved methods on the ancient theory that it more than temporarily deprives men of employment… has no place in the gospel of American progress.”

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“One cannot deny that in former times man's life had been one of toil and hardship. It is correct to say, therefore, that modern civilization and the progress of science have greatly improved man's life and have brought comfort and ease in their trail.”

Haile Selassie (1892–1975) Emperor of Ethiopia

Interview in The Voice of Ethiopia (5 April 1948) http://www.jah-rastafari.com/selassie-words/show-jah-word.asp?word_id=interview.
Context: One cannot deny that in former times man's life had been one of toil and hardship. It is correct to say, therefore, that modern civilization and the progress of science have greatly improved man's life and have brought comfort and ease in their trail. But civilization can serve man both for good as well as for evil purposes. Experience shows that it has invariably brought great dividends to those who use it for good purposes while it has always brought incalculable harm and damnation to those who use it for evil purposes. To make our wills obedient to good influences and to avoid evil, therefore, is to show the greatest wisdom. In order to follow this aim one must be guided by religion. Progress without religion is just like a life surrounded by unknown perils and can be compared to a body without a soul. All human inventions, from the most primitive tool to the modern atom, can help man greatly in his peaceful endeavours. But if they are put to evil purposes they have the capacity to wipe out the human race from the surface of the earth. It is only when the human mind is guided by religion and morality that man can acquire the necessary vision to put all his ingenuous inventions and contrivances to really useful and beneficial purposes.

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“Transition is a complete present which unites the past and the future in a momentary progressive ecstasy, a progressive eternity, a true eternity of eternities, eternal moments.”

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“Jesus is eternally right. History is replete with the bleached bones of nations that refused to listen to him.”

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