Source: Buddy Holly is Alive and Well on Ganymede (1991), p. 114
“A poor relation—is the most irrelevant thing in nature.”
Poor Relations.
Last Essays of Elia (1833)
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Charles Lamb 85
English essayist 1775–1834Related quotes
“Shannon's most radical insight was that meaning was irrelevant.”
Part One, Entropy, Randomness, Disorder, Uncertainty, p. 55
Fortune's Formula (2005)

“Intelligence consists in ignoring things that are irrelevant.”
Source: The Bed of Procrustes: Philosophical and Practical Aphorisms (2010), p. 78
Source: Learning Strategies and Individual Competence (1972), p. 276.

“As for catching Osama, it's irrelevant. Things are going swimmingly in Afghanistan.”
Responding to assertions about problems with Osama bin Laden and Afghanistan on Hannity & Colmes (24 August 2006) - video http://movies.crooksandliars.com/H-C-Coulter-crie.mov
2006

“It is a melancholy truth that even great men have their poor relations.”
Source: Bleak House (1852-1853), Ch. 28
“It was at once a miracle and the most natural thing in the world.”
Source: Kitchen

SGU, Podcast #78 – January 15th, 2007 http://www.theskepticsguide.org/podcast/sgu/78
The Skeptics' Guide to the Universe, Podcast, 2000s