“The material which a scientist actually has at his disposal, his laws, his experimental results, his mathematical techniques, his epistemological prejudices, his attitude towards the absurd consequences of the theories which he accepts, is indeterminate in many ways, ambiguous, and never fully separated from the historical background.”

This material is always contaminated by principles which he does not know and which, if known, would be extremely hard to test.
Pg. 66.
Against Method (1975)

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Paul Karl Feyerabend 81
Austrian-born philosopher of science 1924–1994

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“So many people today — and even professional scientists — seem to me like someone who has seen thousands of trees but has never seen a forest. A knowledge of the historic and philosophical background gives that kind of independence from prejudices of his generation from which most scientists are suffering. This independence created by philosophical insight is — in my opinion — the mark of distinction between a mere artisan or specialist and a real seeker after truth.”

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Context: I fully agree with you about the significance and educational value of methodology as well as history and philosophy of science. So many people today — and even professional scientists — seem to me like someone who has seen thousands of trees but has never seen a forest. A knowledge of the historic and philosophical background gives that kind of independence from prejudices of his generation from which most scientists are suffering. This independence created by philosophical insight is — in my opinion — the mark of distinction between a mere artisan or specialist and a real seeker after truth.

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“The reciprocal relationship of epistemology and science is of noteworthy kind. They are dependent on each other. Epistemology without contact with science becomes an empty scheme. Science without epistemology is — insofar as it is thinkable at all — primitive and muddled. However, no sooner has the epistemologist, who is seeking a clear system, fought his way through to such a system, than he is inclined to interpret the thought-content of science in the sense of his system and to reject whatever does not fit into his system. The scientist, however, cannot afford to carry his striving for epistemological systematic that far. He accepts gratefully the epistemological conceptual analysis; but the external conditions, which are set for him by the facts of experience, do not permit him to let himself be too much restricted in the construction of his conceptual world by the adherence to an epistemological system. He therefore must appear to the systematic epistemologist as a type of unscrupulous opportunist: he appears as realist insofar as he seeks to describe a world independent of the acts of perception; as idealist insofar as he looks upon the concepts and theories as free inventions of the human spirit (not logically derivable from what is empirically given); as positivist insofar as he considers his concepts and theories justified only to the extent to which they furnish a logical representation of relations among sensory experiences. He may even appear as Platonist or Pythagorean insofar as he considers the viewpoint of logical simplicity as an indispensible and effective tool of his research.”

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“In most cases the scientist will be fully aware of the possibility of an abuse of his discoveries, but aside from his innate scientific curiosity he will be motivated by a deep-seated hope and belief that something of value for his fellow man may emerge from his labors.”

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Comparable to remarks of William Masters, in "Two Sex Researchers on the Firing Line" LIFE magazine (24 June 1966), p. 49: "Science by itself has no moral dimension. But it does seek to establish truth. And upon this truth morality can be built."
Variants:
Science does not have a moral dimension. It is like a knife. If you give it to a surgeon or a murderer, each will use it differently.
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Science does not have a moral dimension. It is like a knife. If you give it to a surgeon or a murderer, each will use it differently. Should the knife have not been developed?
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Context: One of the most disconcerting issues of our time lies in the fact that modern science, along with miracle drugs and communications satellites, has also produced nuclear bombs. What makes it even worse, science has utterly failed to provide an answer on how to cope with them. As a result, science and scientists have often been blamed for the desperate dilemma in which mankind finds itself today.
Science, all by itself, has no moral dimension. The same poison-containing drug which cures when taken in small doses, may kill when taken in excess. The same nuclear chain reaction that produces badly needed electrical energy when harnessed in a reactor, may kill thousands when abruptly released in an atomic bomb. Thus it does not make sense to ask a biochemist or a nuclear physicist whether his research in the field of toxic substances or nuclear processes is good or bad for mankind. In most cases the scientist will be fully aware of the possibility of an abuse of his discoveries, but aside from his innate scientific curiosity he will be motivated by a deep-seated hope and belief that something of value for his fellow man may emerge from his labors.
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