“Tell the merchant that he must not rely for one moment on the Home Rulers for any one thing that is wise and good, nor indeed on any political combination of Irishmen. They have never yet done anything for themselves or their country and have never yet as a party shown what ought to be done. The absence of political and economical knowledge in Ireland is remarkable, and what there is of a sensible middle class is apparently crushed or smothered by the extreme men, who are always in pursuit of some phantom and who seem not to know the substance even when they see it.”

Aphorism 6
Novum Organum (1620), Book I

"As I Please," Tribune (24 March 1944)^{http://alexpeak.com/twr/wif/}
"As I Please" (1943–1947)

About King Charles II of England, as quoted in Blackwood's Edinburgh Magazine Vol. XLIV (January - June 1857) p. 592; It is said to that this was written on the door of Charles II’s bedchamber, and that on seeing it, the king replied, “This is very true: for my words are my own, and my actions are my ministers’....”
Other

Speech in Birmingham (19 October 1974) http://www.margaretthatcher.org/document/101830
1970s

Letter to Archbishop of Canterbury (14 October 1940), quoted in Keith Feiling, Neville Chamberlain (London: Macmillan, 1946), p. 455.
Post-Prime Ministerial

Source: A Room of One's Own

Source: A Wild Sheep Chase: A Novel (1982), Chapter 10, Counting Sheep
Context: We can, if we so choose, wander aimlessly over the continent of the arbitrary. Rootless as some winged seed blown about on a serendipitous spring breeze. Nonetheless, we can in the same breath deny that there is any such thing as coincidence. What's done is done, what's yet to be is clearly yet to be. In other words, sandwiched as we are between the "everything" that is behind us and the "zero" beyond us, ours is an ephemeral existence in which there is neither coincidence nor possibility. In actual practice, however, distinctions between the two interpretations amount to precious little. A state of affairs (as with most face-offs between interpretations) not unlike calling the same food by two different names. So much for metaphors.

International Herald Tribune (29 October 1991)
Context: Despite all the political misery I am confronted with every day, it still is my profound conviction that the very essence of politics is not dirty; dirt is brought in only by wicked people. I admit that this is an area of human activity where the temptation to advance through unfair actions may be stronger than elsewhere, and which thus makes higher demands on human integrity. But it is not true at all that a politician cannot do without lying or intriguing. That is sheer nonsense, often spread by those who want to discourage people from taking an interest in public affairs.
Of course, in politics, just as anywhere else in life, it is impossible and it would not be sensible always to say everything bluntly. Yet that does not mean one has to lie. What is needed here are tact, instinct and good taste.

Source: The Passionate Life (1983), pp. 82-83