“No longer is science asked to understand the world, or to improve any part of it. It is asked instead to immediately justify everything that happens…. spectacular domination has cut down the vast tree of scientific knowledge in order to make itself a truncheon.”

Part 2: "The Habit of Truth", §11 (p. 45–46)
Science and Human Values (1956, 1965)
Context: In effect what Luther said in 1517 was that we may appeal to a demonstrable work of God, the Bible, to override any established authority. The Scientific Revolution begins when Nicolaus Copernicus implied the bolder proposition that there is another work of God to which we may appeal even beyond this: the great work of nature. No absolute statement is allowed to be out of reach of the test, that its consequence must conform to the facts of nature.
The habit of testing and correcting the concept by its consequences in experience has been the spring within the movement of our civilization ever since. In science and in art and in self-knowledge we explore and move constantly by turning to the world of sense to ask, Is this so? This is the habit of truth, always minute yet always urgent, which for four hundred years has entered every action of ours; and has made our society and the value it sets on man.

Nature and the Greeks (1954)
Context: The scientific world-picture vouchsafes a very complete understanding of all that happens — it makes it just a little too understandable. It allows you to imagine the total display as that of a mechanical clockwork which, for all that science knows, could go on just the same as it does, without there being consciousness, will, endeavor, pain and delight and responsibility connected with it — though they actually are. And the reason for this disconcerting situation is just this: that for the purpose of constructing the picture of the external world, we have used the greatly simplifying device of cutting our own personality out, removing it; hence it is gone, it has evaporated, it is ostensibly not needed.

The Atheist's Guide to Reality (2011)
Context: There is, however, a much more convincing argument that needs to be put on the table before we really begin turning common sense upside down. It is the overwhelming reason to prefer science to ordinary beliefs, common sense, and direct experience. Science is just common sense continually improving itself, rebuilding itself, until it is no longer recognizable as common sense. It is easy to miss this fact about science without studying a lot of history of science—and not the stories about science, but the succession of actual scientific theories and how common sense was both their mother and their midwife.

Undated attributed quote

Source: War and Peace

Introduction, p. xii
The English Constitution (1867)

Source: The Life of Reason: The Phases of Human Progress (1905-1906), Vol. V, Reason in Science, Ch. 2 "History"
Context: History is nothing but assisted and recorded memory. It might almost be said to be no science at all, if memory and faith in memory were not what science necessarily rest on. In order to sift evidence we must rely on some witness, and we must trust experience before we proceed to expand it. The line between what is known scientifically and what has to be assumed in order to support knowledge is impossible to draw. Memory itself is an internal rumour; and when to this hearsay within the mind we add the falsified echoes that reach us from others, we have but a shifting and unseizable basis to build upon. The picture we frame of the past changes continually and grows every day less similar to the original experience which it purports to describe.

Essay 1, Section 13
On the Genealogy of Morality (1887)