“If you wish to alter or annihilate a pyramid of numbers in a serial relation, you alter or remove the bottom number. If we wish to annihilate the junk pyramid, we must start with the bottom of the pyramid: the Addict in the Street, and stop tilting quixotically for the "higher ups" so called, all of whom are immediately replaceable. The addict in the street who must have junk to live is the one irreplaceable factor in the junk equation. When there are no more addicts to buy junk there will be no junk traffic. As long as junk need exists, someone will service it.”

Prologue
Junkie (1953)

Hauser and O'Brien
Naked Lunch (1959)

Source: Summer of Love (1994), Chapter 15 “Over Under Sideways Down” (p. 329)

Junkie (1953)

Junkie (1953)
Context: When you give up junk, you give up a way of life. I have seen junkies kick and hit the lush and wind up dead in a few years. Suicide is frequent among ex-junkies. Why does a junky quit junk of his own will? You never know the answer to that question. No conscious tabulation of the disadvantages and horrors of junk gives you the emotional drive to kick. The decision to quit junk is a cellular decision, and once you have decided to quit you cannot go back to junk permanently any more than you could stay away from it before.

Source: Top scientists warn of 'ghastly future of mass extinction' and climate disruption https://www.theguardian.com/environment/2021/jan/13/top-scientists-warn-of-ghastly-future-of-mass-extinction-and-climate-disruption-aoe. The Guardian (2021)

Junkie (1953)

Source: On the Jellicoe Road