Francis Crick: Fact

Francis Crick was British molecular biologist, biophysicist, neuroscientist; co-discoverer of the structure of DNA. Explore interesting quotes on fact.
Francis Crick: 32   quotes 0   likes

“I wasn't aware of Chargaff's rules when he said them, but the effect on me was quite electric because I realized immediately that if you had this sort of scheme that John Griffith was proposing, of adenine being paired with thymine, and guanine being paired with cytosine, then you should get Chargaff's rules. I was very excited, but I didn't actually tell Chargaff because it was something I was doing with John Griffith…. This was very exciting, and we thought "ah ha!" and we realized - I mean what anyone who is familiar with the history of science ought to realize - that when you have one-to-one ratios, it means things go to together. And how on Earth no one pointed out this simple fact in those years, I don't know.”

Francis Crick

The DNA Story (1973, film, VSM Productions)

History , Science

“An honest man, armed with all the knowledge available to us now, could only state that in some sense, the origin of life appears at the moment to be almost a miracle, so many are the conditions which would have had to have been satisfied to get it going. But this should not be taken to imply that there are good reasons to believe that it could not have started on the earth by a perfectly reasonable sequence of fairly ordinary chemical reactions. The plain fact is that the time available was too long, the many microenvironments on the earth's surface too diverse, the various chemical possibilities too numerous and our own knowledge and imagination too feeble to allow us to be able to unravel exactly how it might or might not have happened such a long time ago, especially as we have no experimental evidence from that era to check our ideas against.”

Francis Crick

New York NY: Simon & Schuster, 1981, p. 88.
Life Itself: Its Origin and Nature (1981)

Life , Imagination , Idea , Knowledge

“Philosophers have been especially concerned with the problem of consciousness—for example, how to explain the redness of red or the painfulness of pain. This is a very thorny issue. The problem springs from the fact that the redness of red that I perceive so vividly cannot be precisely communicated to another human being, at least in the ordinary course of events. If you cannot describe the properties of a thing unambiguously, you are likely to have some difficulty trying to explain these properties in reductionist terms.”

Francis Crick

The Astonishing Hypothesis (1994)

Pain , Spring , Communication , Problem

“The ultimate aim of the modern movement in biology is in fact to explain all biology in terms of physics and chemistry.”

Francis Crick

Seattle: University of Washington Press, 1966, p. 10.
Of Molecules and Men (1966)

“If for example I had some idea, which as it turned out would be quite wrong, was going off of the tangent, Watson would tell me in no uncertain terms this was nonsense, and vice-versa. If he would have some idea I didn't like, and I would say so, this would shake his thinking about, and draw him back again. And in fact it is one of the requirements for collaborations of this sort, is you must be perfectly candid, one might almost say rude, to the person you're working with. It's useless working with somebody who is either much too junior than yourself or much too senior because then politeness creeps in. And this is the end of all real collaboration in science”

Francis Crick

giggles
The Prizewinners (11 December 1962, BBC)

Idea , Thinking , Science , Drawing

“I argued that it was important not to place too much reliance on any single piece of experimental evidence. It might turn out to be misleading, as the 5.1 Å reflection undoubtedly was. Jim was a little more brash, stating that no good model ever accounted for all the facts, since some data was bound to be misleading if not plain wrong. A theory that did fit all the data would have been "carpentered" to do so and would thus be open to suspicion.”

Francis Crick

Source: What Mad Pursuit (1988), pp. 59-60