Source: The Logic of Scientific Discovery (1934), Ch. 1 "A Survey of Some Fundamental Problems", Section I: The Problem of Induction
Context: A principle of induction would be a statement with the help of which we could put inductive inferences into a logically acceptable form. In the eyes of the upholders of inductive logic, a principle of induction is of supreme importance for scientific method: "… this principle", says Reichenbach, "determines the truth of scientific theories. To eliminate it from science would mean nothing less than to deprive science of the power to decide the truth or falsity of its theories. Without it, clearly, science would no longer have the right to distinguish its theories from the fanciful and arbitrary creations of the poet's mind."
Now this principle of induction cannot be a purely logical truth like a tautology or an analytic statement. Indeed, if there were such a thing as a purely logical principle of induction, there would be no problem of induction; for in this case, all inductive inferences would have to be regarded as purely logical or tautological transformations, just like inferences in inductive logic. Thus the principle of induction must be a synthetic statement; that is, a statement whose negation is not self-contradictory but logically possible. So the question arises why such a principle should be accepted at all, and how we can justify its acceptance on rational grounds.
Quotes from book
The Logic of Scientific Discovery
The Logic of Scientific Discovery is a 1959 book about the philosophy of science by the philosopher Karl Popper. Popper rewrote his book in English from the 1934 German original, titled Logik der Forschung. Zur Erkenntnistheorie der modernen Naturwissenschaft, which literally translates as, "Logic of Research: On the Epistemology of Modern Natural Science"'.
Source: The Logic of Scientific Discovery (1934), Ch. 10 "Corroboration, or How a Theory Stands up to Tests", section 85: The Path of Science, p. 280
Context: Bold ideas, unjustified anticipations, and speculative thought, are our only means for interpreting nature: our only organon, our only instrument, for grasping her. And we must hazard them to win our prize. Those among us who are unwilling to expose their ideas to the hazard of refutation do not take part in the scientific game.
“...non-reproducible single occurrences are of no significance to science.”
Source: The Logic of Scientific Discovery (1934), Ch. 4 "Falsifiability", Section XXII: Falsifiability and Falsification. p. 66.