“Cleverly designed experiments are the key.”
Context: The truth may be puzzling. It may take some work to grapple with. It may be counterintuitive. It may contradict deeply held prejudices. It may not be consonant with what we desperately want to be true. But our preferences do not determine what's true. We have a method, and that method helps us to reach not absolute truth, only asymptotic approaches to the truth — never there, just closer and closer, always finding vast new oceans of undiscovered possibilities. Cleverly designed experiments are the key.
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Carl Sagan 365
American astrophysicist, cosmologist, author and science ed… 1934–1996Related quotes

Source: "Microeconomic systems as an experimental science," 1982, p. 923.

Section 2 : Religion
Founding Address (1876), Life and Destiny (1913)
Context: The symbols of religion are ciphers of which the key is to be found in moral experience. It is in vain we pore over the ciphers unless we possess the key.
To understand the meaning of a great religious teacher we must find in our own life experiences somewhat akin to his. To selfish, unprincipled persons whose heart is wholly set on worldly ends, what meaning, for instance, can such utterances have as these? "You must become like little children if you would possess the kingdom of heaven;" "You must be willing to lose your life in order to save it;" "If you would be first you must consent to be last." To the worldly-minded such words convey no sense whatever; they are, in fact, rank absurdity.?

“Experience has shown that the trade of the East is the key to national wealth and influence.”
Veto message of Chinese Exclusion Act (1882).
1880s
Source: http://www.missnews.com.br/noticias/wareus-rooting-for-miss-botswana "Wareus rooting for Miss Botswana

An interview with gubernatorial candidate Ed Gillespie http://www.fredericksburg.com/sports/outdoors/ken-perrotte-an-interview-with-gubernatorial-candidate-ed-gillespie/article_ac9bcf45-054a-5a84-b7e2-e5214e3209e7.html (October 25, 2017)
Another part of the interview: Also cited at: Mark Wunsch. "[http://markwunsch.com/blog/2008/09/27/design-q-a-with-charles-eames.html A software engineer and technologist: Design Q&A with Charles Eames". at markwunsch.com/blog, 2008/09/27
Design Q & A with Charles Eames, 1972
Source: Tools For Survival (2009), p. 150

Small Houses: Their Economic Design and Construction (1922)