“The emergence of a unified cognitive moment relies on the coordination of scattered mosaics of functionally specialized brain regions. Here we review the mechanisms of large-scale integration that counterbalance the distributed anatomical and functional organization of brain activity to enable the emergence of coherent behaviour and cognition. Although the mechanisms involved in large-scale integration are still largely unknown, we argue that the most plausible candidate is the formation of dynamic links mediated by synchrony over multiple frequency bands.”

Francisco Varela*, Jean-Philippe Lachaux*, Eugenio Rodriguez, and Jacques Martinerie (2001) "The brainweb: phase synchronization and large-scale integration" in: Nature Rviews Vol 2. (April 2001). p. 229 ( online http://www.saminverso.com/brg/archive/varela%202001%20Brainweb-Phase%20synchronization%20and%20large%20scale%20integration.pdf)

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Francisco Varela 17
Chilean biologist 1946–2001

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