“Molecular biology has also shown that the basic design of the cell system is essentially the same in all living systems on earth from bacteria to mammals. In all organisms the roles of DNA, mRNA and protein are identical. The meaning of the genetic code is also virtually identical in all cells. The size, structure and component design of the protein synthetic machinery is practically the same in all cells. In terms of their basic biochemical design, therefore no living system can be thought of as being primitive or ancestral with respect to any other system, nor is there the slightest empirical hint of an evolutionary sequence among all the incredibly diverse cells on earth.”

— Michael Denton , book Evolution: A Theory in Crisis

Source: Evolution: A Theory in Crisis (1986), p. 250

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Michael Denton 6

British-Australian author and biochemist 1943

Michael Denton book Evolution: A Theory in Crisis

Source: Evolution: A Theory in Crisis (1986), p. 250

“… the genetic code is in fact literally identical in all animals, plants and bacteria … All earthly living things are certainly descended from a single ancestor.”

Richard Dawkins (1941) English ethologist, evolutionary biologist and author

River out of Eden (1995)

“… the organization chart will initially reflect the first system design, which is almost surely not the right one [… ] as one learns, he changes the design [… ]. Management structures also need to be changed as the system changes…”

Fred Brooks (1931) American computer scientist

The Mythical Man-Month: Essays on Software Engineering (1975, 1995)

“When it comes to the design of social and societal systems of all kinds, it is the users, the people in the system who are the experts. Nobody has the right to design social systems for someone else. It is unethical to do so. Design cannot be legislated, it should not be bought from the expert, and it should not be copied from the design of others. If the privilege of and responsibility for design is "given away," others will take charge of designing our lives and our systems. They will shape our future.”

Béla H. Bánáthy (1919–2003) Hungarian linguist and systems scientist

Source: Designing Social Systems in a Changing World (1996), p. 128; Cited in: Roberto Joseph et al. (2002) " Banathy's Influence on the Guidance System for Transforming Education http://www.indiana.edu/~syschang/decatur/reigeluth_pubs/documents/95_banathy_influence_on_gste.pdf". World Futures: The Journal of General Evolution, 58(5/6) 379-394

“To explain the origin of the DNA/protein machine by invoking a supernatural Designer is to explain precisely nothing, for it leaves unexplained the origin of the Designer.”

Richard Dawkins book The Blind Watchmaker

Source: The Blind Watchmaker (1986), Chapter 6 “Origins and Miracles” (p. 141)

“[In the year 1957] I have just returned from an exciting meeting of the American Society for Engineering Education where I heard a paper on the new discipline of systems engineering. It is no longer sufficient for engineers merely to design boxes such as computers with the expectation that they would become components of larger, more complex systems. That is wasteful because frequently the box component is a bad fit in the system and has to be redesigned or worse, can lead to system failure. We must learn how to design large-scale, complex systems from the top down so that the specification for each component is derivable from the requirements for the overall system. We must also take a much larger view of systems. We must design the man-machine interfaces and even the system-society interfaces. Systems engineers must be trained for the design of large-scale, complex, man-machine-social systems.”

A. Wayne Wymore (1927–2011) American mathematician

Systems Movement: Autobiographical Retrospectives (2004)

“The fallacy of genetic determinism is to suppose that the genes "make" the organism. It is a basic principle of developmental biology that organisms undergo a continuous development from conception to death, a development that is the unique consequence of the interaction of the genes in their cells, the temporal sequence of environments through which the organisms pass, and random cellular processes that determine the life, death, and transformation of cells. As a result, even the fingerprints of identical twins are not identical. Their temperaments, mental processes, abilities, life choices, disease histories, and death certainly differ despite the determined efforts of many parents to enforce as great a similarity as possible.”

Richard C. Lewontin (1929) American evolutionary biologist

" The Confusion over Cloning http://www.nybooks.com/articles/archives/1997/oct/23/the-confusion-over-cloning/," The New York Review of Books, 23 October 1997.
Review of Cloning Human Beings: Report and Recommendations of the National Bioethics Advisory Commission by the National Bioethics Advisory Commission.

“The techniques of the practitioner are usually called 'synthetic'. He designs by organizing known principles and devices into larger systems.”

Herbert A. Simon (1916–2001) American political scientist, economist, sociologist, and psychologist

Simon (1945, p. 353); As cited in: Philosophy of Technology and Engineering Sciences (2009) p. 425.
1940s-1950s

“In some regions, under especially favorable conditions, the level of organization reaches that of enormously heavy organic substances, such as protein molecules and nucleic acids. Now the basic building blocks are given for the constitution of self-replicating units of still higher organizational level: cells. These systems maintain a constant flow of substances through their structures, imposing on it a steady-state with specific parameters. The inputs and outputs may achieve coordination with analogous units in the surrounding medium, and we are on our way toward multicellular phenomena. The resulting structures — organisms — are likewise steady-state patterns imposed steady-state patterns imposed on a continuous flow… The organic systems themselves, define the supra-organic (ecological or social) community. Ultimately the strands of communication straddle the space-time region within which the primary systems have come together, and those of its layers which provide conditions favorable to such structuration become organized as systems in their own right. We reach the level of the global (ecological, and on earth also sociocultural) system.”

Ervin László (1932) Hungarian musician and philosopher

Source: Introduction to Systems Philosophy (1972), p. 83.

“At the molecular level, we are all virtually identical.”

Carl Sagan (1934–1996) American astrophysicist, cosmologist, author and science educator

The Varieties of Scientific Experience: A Personal View of the Search for God (2006)
Context: When you look more generally at life on Earth, you find that it is all the same kind of life.... It uses about fifty fundamental biological building blocks, organic molecules.... with trivial exceptions, all organisms on Earth use... an enzyme, to control the rate and direction of the chemistry of life.... a nucleic acid to encode the hereditary information... the identical code book for translating nucleic acid language into protein language.... At the molecular level, we are all virtually identical.

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