“Even though I had long been taught that the genes of the brain are the governors of behavior, the absolute masters of our fate, our work showed that, in the brain as in bacteria, genes are also servants of the environment.”

“Jacob and Monod not only outlined a theory of gene regulation, they also discovered the first regulators of gene transcription. These regulators come in two forms—repressors, genes that encode the regulatory proteins that shut genes off, and as later work showed, activators, genes that encode the regulatory proteins that turn genes on.”

“Right now, at my institute in the US we are working on gene-caused failures in brain development that frequently lead to autism and schizophrenia. We may also find that differences in these respective brain development genes also lead to differences in our abilities to carry out different mental tasks.
In some cases, how these genes function may help us to understand variations in IQ, or why some people excel at poetry but are terrible at mathematics. All too often people with high mathematical abilities have autistic traits. The same gene that gives some people such great mathematical abilities may also lead to autistic behaviour. This is why, in studying autism and schizophrenia, we believe that we shall come very close to a better understanding of intelligence and, therefore, of the differences in intelligence.”

“Jacob and Monod found that in bacteria, genes are switched on and off by other genes. This led them to distinguish between effector genes and regulatory genes. Effector genes encode effector proteins… which mediate specific cellular functions. Regulatory genes encode proteins called regulatory proteins, which switch the effector genes on or off.”

“I believe there is a reason such as autism, severe manic-depression, and schizophrenia remain in our gene pool even though there is much suffering as a result.”

“But here I stop—short of any deterministic speculation that attributes specific behaviors to the possession of specific altruist or opportunist genes. Our genetic makeup permits a wide range of behaviors—from Ebenezer Scrooge before to Ebenezer Scrooge after. I do not believe that the miser hoards through opportunist genes or that the philanthropist gives because nature endowed him with more than the normal complement of altruist genes. Upbringing, culture, class, status, and all the intangibles that we call “free will,” determine how we restrict our behaviors from the wide spectrum—extreme altruism to extreme selfishness—that our genes permit.”

“When you eat a healthy, whole foods, plant-based diet, it changes the expression of your genes. It turns on the good genes, turns off the bad genes. Your genes are a predisposition, but your genes are not your fate. And even if your mother and your father and aunts and uncles all died of diabetes, cancer, even heart disease, it doesn't mean that you need to.”

“We can actually change the expression of genes—tumor suppressing genes, tumor activating genes—by what we eat, what we put into our bodies. So, even if you've been dealt a bad genetic deck, you can still reshuffle it with diet.”

“It is an article of passionate faith among "politically correct" biologists and anthropologists that brain size has no connection with intelligence; that intelligence has nothing to do with genes; and that genes are probably nasty fascist things anyway.”

“We have magnificent brains—and use them to believe nonsense and behave as fools. . . . We are enslaved to delusions and too often the servants of subconscious biases. . . . Our great challenge is to use our brains to overcome our brains.”