“Nobilities, indecencies, heroic impulses, cowardly ravings, good and bad, white and black — the mystery of mysteries, the central island of nescience in a sea of science, the dark spot in the lighted room of knowledge, the unknown quantity, the X in the universal problem.”
Four Minute Essays Vol. 5 (1919), The Human Heart
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Frank Crane 38
American Presbyterian minister 1861–1928Related quotes

“Science has only increased the area of the unknown. And if there is a God, her name is Mystery.”
Source: Our Lady of Darkness (1977), Chapter 8 (p. 43)

First published in the "Movie Answer Man" column (25 July 2004) http://rogerebert.suntimes.com/apps/pbcs.dll/article?AID=/20040725/ANSWERMAN/407250305
Context: Many moviegoers and video viewers say they do not "like" black and white films. In my opinion, they are cutting themselves off from much of the mystery and beauty of the movies.
Black and white is an artistic choice, a medium that has strengths and traditions, especially in its use of light and shadow. Moviegoers of course have the right to dislike b&w, but it is not something they should be proud of. It reveals them, frankly, as cinematically illiterate.
I have been described as a snob on this issue. But snobs exclude; they do not include. To exclude b&w from your choices is an admission that you have a closed mind, a limited imagination, or are lacking in taste.

“There's always fear of the unknown where there's mystery.”
McKenna interview (1992)
Context: There's always fear of the unknown where there's mystery. It's possible to achieve a state where you realize the truth of life and fear disappears, and a lot of people have reached that state, but next to none of them are on Earth. There's probably a few.

“In a world of diminishing mystery, the unknown persists.”
Source: The Lowland
The Hidden Wisdom In The Holy Bible (1963), Volume III

Part of this quote may actually be by Ralph Washington Sockman.
The World's Religions (1991)
Source: Beyond the Post-Modern Mind: The Place of Meaning in a Global Civilization
Context: In mysteries what we know, and our realization of what we do not know, proceed together; the larger the island of knowledge, the longer the shoreline of wonder. It is like the quantum world, where the more we understand its formalism, the stranger that world becomes.