“The great problem facing modern man is that, that the means by which we live have outdistanced the spiritual ends for which we live. So we find ourselves caught in a messed-up world. The problem is with man himself and man's soul. We haven't learned how to be just and honest and kind and true and loving. And that is the basis of our problem. The real problem is that through our scientific genius we've made of the world a neighborhood, but through our moral and spiritual genius we've failed to make of it a brotherhood.”

1960s, Keep Moving From This Mountain (1965)
Context: We have allowed our civilization to outrun our culture; we have allowed our technology to outdistance our theology and for this reason we find ourselves caught up with many problems. Through our scientific genius we made of the world a neighborhood, but we failed through moral commitment to make of it a brotherhood, and so we’ve ended up with guided missiles and misguided men. And the great challenge is to move out of the mountain of practical materialism and move on to another and higher mountain which recognizes somehow that we must live by and toward the basic ends of life. We must move on to that mountain which says in substance, "What doth it profit a man to gain the whole world of means — airplanes, televisions, electric lights — and lose the end: the soul?"

1960s, The Quest for Peace and Justice (1964)
Context: Every man lives in two realms, the internal and the external. The internal is that realm of spiritual ends expressed in art, literature, morals, and religion. The external is that complex of devices, techniques, mechanisms, and instrumentalities by means of which we live. Our problem today is that we have allowed the internal to become lost in the external. We have allowed the means by which we live to outdistance the ends for which we live. So much of modern life can be summarized in that arresting dictum of the poet Thoreau: "Improved means to an unimproved end". This is the serious predicament, the deep and haunting problem confronting modern man. If we are to survive today, our moral and spiritual "lag" must be eliminated. Enlarged material powers spell enlarged peril if there is not proportionate growth of the soul. When the "without" of man's nature subjugates the "within", dark storm clouds begin to form in the world.

1950s, Rediscovering Lost Values (1954)
Context: There is something wrong with our world, something fundamentally and basically wrong. I don't think we have to look too far to see that. I'm sure that most of you would agree with me in making that assertion. And when we stop to analyze the cause of our world's ills, many things come to mind. We begin to wonder if it is due to the fact that we don't know enough. But it can't be that. Because in terms of accumulated knowledge we know more today than men have known in any period of human history. We have the facts at our disposal. We know more about mathematics, about science, about social science, and philosophy than we've ever known in any period of the world's history. So it can't be because we don't know enough. And then we wonder if it is due to the fact that our scientific genius lags behind. That is, if we have not made enough progress scientifically. Well then, it can't be that. For our scientific progress over the past years has been amazing. Man through his scientific genius has been able to dwarf distance and place time in chains, so that today it's possible to eat breakfast in New York City and supper in London, England. Back in about 1753 it took a letter three days to go from New York City to Washington, and today you can go from here to China in less time than that. It can't be because man is stagnant in his scientific progress. Man's scientific genius has been amazing. I think we have to look much deeper than that if we are to find the real cause of man's problems and the real cause of the world's ills today. If we are to really find it I think we will have to look in the hearts and souls of men.

Why our future depends on libraries, reading and daydreaming (2013)

Said in a Fox Business interview https://www.facebook.com/FoxBusiness/posts/weve-been-conditioned-to-think-that-only-politicians-can-solve-our-problems-but-/10153892947535238/ (February 9, 2016)

1950s, Rediscovering Lost Values (1954)

Undated attributed quote

The Mexican-American and the Church (1968)