“I believe synthetic biology forces society into the chaos of ethics. And, I believe that every connotation of "chaos" applies to the ethics of synthetic biology. Researchers must decide if a particular endeavor is ethical because, of course, mistakes can result due to the unpredictability of these very complex systems. I also believe that the original Greek and the Genesis, Chapter 1, understanding of formlessness applies, since scientists are trying to move to the simplest creatures possible, so-called "chassis bacteria", onto which they can add desirable traits at their choosing. Finally, I believe that the mathematical connotation of chaos applies, since even the most simple living creature is a dynamical system that is highly sensitive to initial conditions. I sometimes wonder about the extent to which those most intimately involved and those strongly advocating synthetic biology think about this.”

Class notes from Vallero's optimization course at Duke University. 2017.

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American scientist 1953

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