“What is found in biology is mechanisms, mechanisms built with chemical components and that are often modified by other, later, mechanisms added to the earlier ones. While Occam's razor is a useful tool in the physical sciences, it can be a very dangerous implement in biology. It is thus very rash to use simplicity and elegance as a guide in biological research. While DNA could be claimed to be both simple and elegant, it must be remembered that DNA almost certainly originated fairly close to the origin of life when things were necessarily simple or they would not have got going.
Biologists must constantly keep in mind that what they see was not designed, but rather evolved. It might be thought, therefore, that evolutionary arguments would play a large part in guiding biological research, but this is far from the case. It is difficult enough to study what is happening now. To figure out exactly what happened in evolution is even more difficult. Thus evolutionary achievements can be used as hints to suggest possible lines of research, but it is highly dangerous to trust them too much. It is all too easy to make mistaken inferences unless the process involved is already very well understood.”
What Mad Pursuit (1988)
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Francis Crick 16
British molecular biologist, biophysicist, neuroscientist; … 1916–2004Related quotes

Source: A machine that learns (1951), p. 60.
Principles of Biochemistry, Ch. 1 : The Foundations of Biochemistry

Source: On Building Systems That Will Fail (1991), p. 80

“The mechanical danger must be overcome by a mechanical remedy”
The World Crisis, 1915 : Chapter I (The Deadlock in the West), Churchill, Butterworth (1923), pp. 22-23.
Early career years (1898–1929)
Context: Mechanical not less than strategic conditions had combined to produce at this early period in the war a deadlock both on sea and land. The strongest fleet was paralysed in its offensive by the menace of the mine and the torpedo. The strongest army was arrested in its advance by the machine gun...... The mechanical danger must be overcome by a mechanical remedy..... Something must be discovered which would render ships immune from the torpedo, and make it unnecessary for soldiers to bare their breasts to the machine-gun hail.

“The Book of the science of Mechanics must precede the Book of useful inventions.”
The Notebooks of Leonardo da Vinci (1883), I Prolegomena and General Introduction to the Book on Painting

The Cosmic Philosophy, 1931

What Mad Pursuit (1988)
Introduction
Higher Mathematics for Chemical Students (1911)