“In recent years, the studies of the effects of drugs on the behavior of animals have been playing an increasingly important role. Animal studies have been an advantage over studies with human subjects because better control of experimental variables and a possibility of using a wider range of the doses. It is also permissible to administer toxix compounds to animals. One can interfere surgically with various parts of the central nervous system while investigating the effects of the drugs. The whole field of comparative psychopharmacology has been recently reviewed”

— Thaddus E. Weckowicz

Weckowicz (1967) "Chapter VI - Animal Studies of Hallucinogenic Drugs" in: Abram Hoffer, Humphry Osmond (1967) The hallucinogens. p. 555

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Thaddus E. Weckowicz22

Canadian psychologist 1919–2000

Deborah Mayo American philosopher

Source: Against a Scientific Justification of Animal Experiments, p. 351

“Arguments to the effect that it is wrong to cause pain and suffering to animals are often rejected by claiming that animals simply do not suffer. … Ironically, it is precisely upon the assumption that animals do suffer from stress, fear, and pain in a manner similar to humans that the validity of much of animal experimentation rests. Few, if any, conditions are studied as widely in animals as are pain, stress, ulcers, fear, and anxiety.”

Deborah Mayo American philosopher

Source: Against a Scientific Justification of Animal Experiments, pp. 345-346

“Scientists, animated by the purpose of proving they are purposeless, constitute an interesting subject for study.”

Alfred North Whitehead (1861–1947) English mathematician and philosopher

The Function of Reason (1929), Beacon Books, 1958, p. 16
1920s

“Our study [China Diet and Health Study] suggests that the closer one approaches a total plant food diet, the greater the health benefit. … It turns out that animal protein, when consumed, exhibits a variety of undesirable health effects. Whether it is the immune system, various enzyme systems, the uptake of carcinogens into the cells, or hormonal activities, animal protein generally only causes mischief. High fat intake still can be a problem, and we ought not to be consuming such high-fat diets. But I suggest that animal protein is more problematic in this whole diet/disease relationship than is total fat.”

T. Colin Campbell (1934) American biochemist

Interview, 1994; as quoted in Souls Like Ourselves by Andrea Wiebers and David Wiebers (Rochester, MN: Sojourn Press, 2000), p. 51.

“For a large number of problems there will be some animal of choice or a few such animals on which it can be most conveniently studied.”

August Krogh (1874–1949) Danish physiologist

A. Krogh (1929). The progress of physiology, American Journal of Physiology 90:243–251.
See Krogh Principle
Famously quoted by an important microbiologist in: Krebs H. A. (1975). The August Krogh Principle: "For many problems there is an animal on which it can be most conveniently studied." Journal of Experimental Zoology 194:221–226.

“A mechanistic model has the following advantages:
1. It contributes to our scientiﬁc understanding of the phenomenon under study.
2. It usually provides a better basis for extrapolation (at least to conditions worthy of further experimental investigation if not through the entire range of all input variables).
3. It tends to be parsimonious (i. e, frugal) in the use of parameters and to provide better estimates of the response”

George E. P. Box (1919–2013) British statistician

Source: Empirical Model-Building and Response Surfaces (1987), p. 13-14 as cited in: Andrew Odlyzko (2010) Social Networks and Mathematical Models http://www.dtc.umn.edu/~odlyzko/doc/ecra.westland.pdf Electronic Commerce Research and Applications 9(1): 26-28 (2010)

“Animation is not just for children - it's also for adults who take drugs.”

Paul McCartney (1942) English singer-songwriter and composer

“I have been studying the traits and dispositions of the "lower animals" (so called) and contrasting them with the traits and dispositions of man. I find the result humiliating to me.”

Mark Twain (1835–1910) American author and humorist

Source: Letters from the Earth: Uncensored Writings

“A general semiotics studies the whole of the human signifying activity — languages — and languages are what constitutes human beings as such, that is, as semiotic animals. It studies and describes languages through languages.”

Umberto Eco book Semiotics and the Philosophy of Language

[O] : Introduction, 0.8
Semiotics and the Philosophy of Language (1984)
Context: A general semiotics studies the whole of the human signifying activity — languages — and languages are what constitutes human beings as such, that is, as semiotic animals. It studies and describes languages through languages. By studying the human signifying activity it influences its course. A general semiotics transforms, for the very fact of its theoretical claim, its own object.

“Misleading may be the claims that procedures [of animal testing] are carried out under anaesthesia. Restraining devices and paralysing drugs can today be so effective that an anaesthetic is often unnecessary from the purely practical point of view. The risk of giving a dose too large and thereby losing an expensive chimpanzee, for example, may often tempt a scientist or technician, inexperienced with sophisticated anaesthetic techniques, to give a dose too small, from which the animal quickly recovers — but not of course until after it has been strapped securely to the operating table.”

Richard D. Ryder (1940) British psychologist

Experiments on Animals (1971)

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