“This misplacing hath caused a deficience, or at least a great improficience in the sciences themselves. For the handling of final causes, mixed with the rest in physical inquiries, hath intercepted the severe and diligent inquiry of all real and physical causes, and given men the occasion to stay upon these satisfactory and specious causes, to the great arrest and prejudice of further discovery. For this I find done not only by Plato, who ever anchoreth upon that shore, but by Aristotle, Galen, and others which do usually likewise fall upon these flats of discoursing causes.”

Book VII, 7
The Advancement of Learning (1605)

Strange Horizons interview (2008)
Context: The Inquisition, by defining and limiting knowledge, was evil. The Taliban, by defining truth and refusing girls an education, is evil. Any religion that says it knows the one and only truth is evil, because it limits knowledge. Any political body that says it owns the truth is evil. Same reason.
Any repressive regime that seeks to control exploration and experimentation is evil. Same reason. Any regime that defines truth as a set of beliefs and occurrences that cannot be questioned, that can neither be demonstrated nor proven is not only evil but ridiculous. This includes all mythologies, miracles, etc. because, if creation happened for a reason, if it was done by God, you'd better believe every part of it, including intelligence, was done for a reason ascertainable, eventually, by intelligence. We would not follow and adore a ruler who lied and tortured. Why would we worship a God who did either? God doesn't lie and he/she/it doesn't fool around!
Shutting down inquiry is evil. Causing pain purposefully for no reason is evil. Enjoying causing pain by shutting down inquiry is an absolute evil.

Source: Five Questions Concerning the Mind (1495), p. 201

Section 4, member 2, subsection 3, Causes of Despair, the Devil, Melancholy, Meditation, Distrust, Weakness of Faith, Rigid Ministers, Misunderstanding Scriptures, Guilty Consciences, etc.
The Anatomy of Melancholy (1621), Part III

Source: Ages in Chaos (2003), Chapter 5, “The Earth’s blood is the veins of its waters” (p. 43)

Source: Speech in the Star Chamber at the censure of John Bastwick, Henry Burton and William Prynne (16 June 1637), quoted in The Works of the Most Reverend Father in God, William Laud, sometime Lord Archbishop of Canterbury. Volume VI: Part I (1847), p. 42

1770s, Common Sense (1776)
Context: The cause of America is in a great measure the cause of all mankind. Many circumstances hath, and will arise, which are not local, but universal, and through which the principles of all Lovers of Mankind are affected, and in the Event of which, their Affections are interested. The laying a Country desolate with Fire and Sword, declaring War against the natural rights of all Mankind, and extirpating the Defenders thereof from the Face of the Earth, is the Concern of every Man to whom Nature hath given the Power of feeling; of which Class, regardless of Party Censure, is the AUTHOR.

The Thirteenth Revelation, Chapter 28

"A Time for Moral Courage", Reader’s Digest (July 1964)