“Human beings have faculties more elevated than the animal appetites, and when once made conscious of them, do not regard anything as happiness which does not include their gratification. I do not, indeed, consider the Epicureans to have been by any means faultless in drawing out their scheme of consequences from the utilitarian principle. To do this in any sufficient manner, many Stoic, as well as Christian elements require to be included. But there is no known Epicurean theory of life which does not assign to the pleasures of the intellect, of the feelings and imagination, and of the moral sentiments, a much higher value as pleasures than to those of mere sensation.”

Speech in the U.S. Senate (2017)
Context: When a leader correctly identifies real hurt and insecurity in our country, and instead of addressing it, goes to look for someone to blame, there is perhaps nothing more devastating to a pluralistic society. Leadership knows that most often a good place to start in assigning blame is to look somewhat closer to home. Leadership knows where the buck stops.Humility helps, character counts. Leadership does not knowingly encourage or feed ugly or debased appetites in us. Leadership lives by the American creed, “E pluribus unum.” From many one. American leadership looks to the world and just as Lincoln did, sees the family of man. Humanity is not a zero sum game. When we have been at our most prosperous, we have been at our most principled, and when we do well, the rest of the world does well.

What is Religion? (1893)

Source: Modern Man in Search of a Soul (1933), p. 69
Context: The great decisions of human life have as a rule far more to do with the instincts and other mysterious unconscious factors than with conscious will and well-meaning reasonableness. The shoe that fits one person pinches another; there is no recipe for living that suits all cases. Each of us carries his own life-form—an indeterminable form which cannot be superseded by any other.

Quoted in Clarence P. Dresser, "Vanderbilt in the West" New York Times (9 October 1882). Dresser's account has Vanderbilt denying that he ran a particular passenger express service for the public benefit, but rather to drive down prices of a competing Pennsylvania Railroad service. By some accounts Dresser fabricated the interview except for the first sentence, which Vanderbilt said in refusing to give an interview. See "Reporter C. P. Dresser Dead", New York Times (25 April 1891).
Disputed

If we theoretically know what a human being is, but someone has never seen one, or if you have never had a relationship with a human being, you cannot know anything about human beings! I think that the best way to gain knowledge is through gaining experience and through connections... Look, if I approach an instrument theoretically, it will give me a theory, so therefore this will make cold music".
1979

On conventional doctrines of Jesus Christ's atonement for sins, in Part II : Opinions Relating to the Doctrine of Atonement, Introduction
An History of the Corruptions of Christianity (1782)

Outline of a Morality Without Obligation or Sanction https://www.marxists.org/archive/guyau/1885/morality.htm (1885).
Context: A third equivalent of duty is borrowed from sensibility and not, like the preceding, from intelligence and activity. It’s the growing fusion of sensibilities, and the ever increasing sociable character of elevated pleasures, from which results a kind of duty or superior necessity which pushes us naturally and rationally towards others. By virtue of evolution, our pleasures grow and become increasingly impersonal; we cannot experience enjoyment within our selves as if on a deserted isle. Our milieu, to which we better adapt ourselves every day, is human society, and we can no more be happy outside of this milieu than we can breathe outside the air. The purely selfish happiness of certain Epicureans is a chimera, an abstraction, an impossibility; the true human pleasures are all more or less social. Pure egoism, rather than being an affirmation of the self, is a mutilation of the self.

The Snow Leopard (1978)
Context: The progress of the sciences toward theories of fundamental unity, cosmic symmetry (as in the unified field theory) — how do such theories differ, in the end, from that unity which Plato called “unspeakable” and “indiscribable,” the holistic knowledge shared by so many peoples of the earth, Christians included, before the advent of the industrial revolution made new barbarians of the peoples of the West? In the United States, before spiritualist foolishness at the end of the last century confused mysticism with “the occult” and tarnished both, William James wrote a master work of metaphysics; Emerson spoke of “the wise silence, the universal beauty, to which every part and particle is equally related, the eternal One . . .”; Melville referred to “that profound silence, that only voice of God”; Walt Whitman celebrated the most ancient secret, that no God could be found “more divine than yourself.” And then, almost everywhere, a clear and subtle illumination that lent magnificence to life and peace to death was overwhelmed in the hard glare of technology. Yet that light is always present, like the stars of noon. Man must perceive it if he is to transcend his fear of meaningless, for no amount of “progress” can take its place. We have outsmarted ourselves, like greedy monkeys, and now we are full of dread.