“The predictions of physical theories for the most part concern situations where initial conditions can be precisely specified. If such initial conditions are not found in nature, they can be arranged. Such arrangements are considerably easier to realize with inanimate than with animate matter, because the properties of animate matter are much more sensitive to being tampered with than inanimate matter. In particular, living tissue in vitro may behave quite differently than in situ. Controlled biological experiments are, of course, possible, but they are more difficult and their scope is more limited than that of physical experiments. For this reason, biology has had to depend to a greater extent than physics on theories of larger speculative scope, in which reasoning by imaginative analogy plays a more important role.”

—  Anatol Rapoport

Anatol Rapoport (1956) "The Search for Simplicity"
1950s

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Anatol Rapoport 45
Russian-born American mathematical psychologist 1911–2007

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