“These little things are very significant.”

Source: Dictionary of Burning Words of Brilliant Writers (1895), P. 561.

Tertium Organum (1922)
Context: Generally speaking, the significance of the indirect results may very often be of more importance than the significance of direct ones. And since we are able to trace how the energy of love transforms itself into instincts, ideas, creative forces on different planes of life; into symbols of art, song, music, poetry; so can we easily imagine how the same energy may transform itself into a higher order of intuition, into a higher consciousness which will reveal to us a marvelous and mysterious world.
In all living nature (and perhaps also in that which we consider as dead) love is the motive force which drives the creative activity in the most diverse directions.

G 46
Variant translation: The inclination of people to consider small things as important has produced many great things.
Aphorisms (1765-1799), Notebook G (1779-1783)

Source: Responsible Servants https://www.sermoncentral.com/sermons/responsible-servants-arulselvam-rayappan-sermon-on-parable-general-77029 (7 March 2005)

"On Elementary Instruction in Physiology" (1877) http://aleph0.clarku.edu/huxley/CE3/ElPhys.html
1870s
Context: The saying that a little knowledge is a dangerous thing is, to my mind, a very dangerous adage. If knowledge is real and genuine, I do not believe that it is other than a very valuable possession, however infinitesimal its quantity may be. Indeed, if a little knowledge is dangerous, where is the man who has so much as to be out of danger?

essay, first appeared in The Atlantic Monthly (November, 1945)
The Simple Art of Murder (1950)

Introduction On Taste
A Philosophical Enquiry into the Origin of Our Ideas of the Sublime and Beautiful (1757)

Source: The Perks of Being a Wallflower

Quoted in Brad Cook, "John Carmack: Making the Magic Happen" http://www.apple.com/games/articles/2009/02/johncarmack/ Apple.com