“To understand events as experienced by actual men and institutions we must be concerned with the history of errors and false starts as well as successes-although we make this distinction on the basis of what we now know of the tradition of success. As we go back in time the uncertainty of the outlook and of the objectives of scientific inquiries increases. The essence of the scientific movement is research. The answers to the essential question, what to do in scientific research-what questions to put to nature, by what methods to get answers, what to count as satisfactory answers-became clear only by the accumulation of successes and the marking of failures.”

— Alistair Cameron Crombie

A. C. Crombie, 1963. as cited in: Robert Maxwell Young. Mind, Brain, and Adaptation in the Nineteenth Century, 1970. p. 101.

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Alistair Cameron Crombie8

Australian zoologist, historian of science 1915–1996

Susanne K. Langer (1895–1985) American philosopher

Feeling and Form, ch. 1, Scribner (1953)

“We often frame our understanding of what the space telescope will do in terms of what we expect to find, and actually it would be terribly anticlimactic if in fact we find what we expect to find. … The most important discoveries will provide answers to questions that we do not yet know how to ask and will concern objects we have not yet imagined.”

John N. Bahcall (1934–2005) American physicist

John N. Bahcall, quoted in his obituary at CalTech (7 September 2005) http://www.spitzer.caltech.edu/features/articles/20050907.shtml; On the Hubble Space Telescope's capabilities for the advancement of science

“Scientific truth was going to make us so happy and comfortable. What actually happened when I was twenty-one was that we dropped scientific truth on Hiroshima.”

Kurt Vonnegut (1922–2007) American writer

Bennington College address (1970)
Context: I thought scientists were going to find out exactly how everything worked, and then make it work better. I fully expected that by the time I was twenty-one, some scientist, maybe my brother, would have taken a color photograph of God Almighty — and sold it to Popular Mechanics magazine.
Scientific truth was going to make us so happy and comfortable. What actually happened when I was twenty-one was that we dropped scientific truth on Hiroshima.

“It is a question of relativity. In order to understand it more clearly we must cleanse our minds of old ideas instilled into us by false education, both religious and scientific, and philosophic too”

Gottfried de Purucker (1874–1942) Author, Theosophist

Ch 2
Man in Evolution (1941)

“a) The definition of history? Every historian would agree, I think, that history is a kind of research or inquiry. What kind of inquiry it is I do not yet ask. The point is that generically it belongs to what we call the sciences: that is, the forms of thought whereby we ask questions and try to answer them. Science in general, it is important to realize, does not consist in collecting what we already know and arranging it in this or that kind of pattern. It consists in fastening upon something we do not know, and trying to discover it. Playing patience with things we already know may be a useful means towards this end, but it is not the end itself. It is at best only the means. It is scientifically valuable only in so far as the new arrangement gives us the answer to a question we have already decided to ask. That is why all science begins from the knowledge of our own ignorance: not our ignorance of everything, but our ignorance of some definite thing-the origin of parliament, the cause of cancer, the chemical composition of the sun, the way to make a pump work without muscular exertion on the part of a man or a horse or some other docile animal. Science is finding things out: and in that sense history is a science.”

R. G. Collingwood (1889–1943) British historian and philosopher

Source: The Idea of History (1946), p. 9

“It seems to me that we must make a distinction between what is "objective" and what is "measurable" in discussing the question of physical reality, according to quantum mechanics.”

Roger Penrose book The Emperor's New Mind

Source: The Emperor's New Mind (1989), Ch. 6, Quantum Magic and Quantum Mastery, p. 269.
Context: It seems to me that we must make a distinction between what is "objective" and what is "measurable" in discussing the question of physical reality, according to quantum mechanics. The state-vector of a system is, indeed, not measurable, in the sense that one cannot ascertain, by experiments performed on the system, precisely (up to proportionality) what the state is; but the state-vector does seem to be (again up to proportionality) a completely objective property of the system, being completely characterized by the results it must give to experiments that one might perform.