
Original Latin: Veritatem inquirenti, semel in vita de omnibus, quantum fieri potest, esse dubitandum
Variant translation: If you would be a real seeker after truth, you must at least once in your life doubt, as far as possible, all things.
Principles of Philosophy (1644)
Variant: In order to seek truth, it is necessary once in the course of our life, to doubt, as far as possible, of all things.