Attributed without citation in Janice R. Matthews et al. (2000) Successful Scientific Writing. p. 53
Sometimes attributed to Douglas Adams.
“You know that fiction, prose rather, is possibly the roughest trade of all in writing. You do not have the reference, the old important reference. You have the sheet of blank paper, the pencil, and the obligation to invent truer than things can be true.”
Letter to Bernard Berenson (24 September 1954); published in Ernest Hemingway: Selected Letters 1917–1961 (1981) edited by Carlos Baker
Context: You know that fiction, prose rather, is possibly the roughest trade of all in writing. You do not have the reference, the old important reference. You have the sheet of blank paper, the pencil, and the obligation to invent truer than things can be true. You have to take what is not palpable and make it completely palpable and also have it seem normal and so that it can become a part of experience of the person who reads it.
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Ernest Hemingway 501
American author and journalist 1899–1961Related quotes

A Letter from Cuba (1934)
Context: The hardest thing to do is to write straight honest prose on human beings. First you have to know the subject; then you have to know how to write. Both take a lifetime to learn, and anybody is cheating who takes politics as a way out. All the outs are too easy, and the thing itself is too hard to do.

Paris Review interview (1958)
Context: From things that have happened and from things as they exist and from all things that you know and all those you cannot know, you make something through your invention that is not a representation but a whole new thing truer than anything true and alive, and you make it alive, and if you make it well enough, you give it immortality. That is why you write and for no other reason that you know of. But what about all the reasons that no one knows?

“All you have to do is write one true sentence. Write the truest sentence you know.”
Source: A Moveable Feast (1964), Ch. 2
Context: I would stand and look out over the roofs of Paris and think, "Do not worry. You have always written before and you will write now. All you have to do is write one true sentence. Write the truest sentence you know."
Introduction, p. vii.
On Writing Well (Fifth Edition, orig. pub. 1976)

Books, What's So Great About America (2003)