“Fermat died with the belief that he had found a long-sought-for law of prime numbers in the formula 2^{2^n} + 1 = a prime, but he admitted that he was unable to prove it rigorously. The law is not true, as was pointed out by Euler in the example 2^{2^5} + 1 = 4,294,967,297 = 6,700,417 times 641. The American lightning calculator Zerah Colburn, when a boy, readily found the factors but was unable to explain the method by which he made his marvellous mental computation.”

Source: A History of Mathematics (1893), p. 180; also cited in Moritz, Memorabilia Mathematica; Or, The Philomath's Quotation-book (1914) pp. 156-157. https://books.google.com/books?id=G0wtAAAAYAAJ&pg=PA156

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Florian Cajori 13
American mathematician 1859–1930

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