“The discipline, nonetheless, is exacting: everything that can be observed should be observed, even if it is only recalled as the bland background from which the intriguing bits pop out like Venus in the evening sky. The goal is always finding something new, hopefully unimagined and, better still, hitherto unimaginable.”
Nobel lecture, 2001
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K. Barry Sharpless 4
American chemist 1941Related quotes
Young Men and Fire (1992)

“Murder had a blood red door on the other side of which was everything unimaginable to everyone.”
Source: The Lovely Bones

“We find that the Romans owed the conquest of the world to no other cause than continual military training, exact observance of discipline in their camps and unwearied cultivation of the other arts of war.”
Nulla enim alia re uidemus populum Romanum orbem subegisse terrarum nisi armorum exercitio, disciplina castrorum usuque militiae.
De Re Militari (also Epitoma Rei Militaris), Book I, "The Selection and Training of New Levies"
Context: Victory in war does not depend entirely upon numbers or mere courage; only skill and discipline will insure it. We find that the Romans owed the conquest of the world to no other cause than continual military training, exact observance of discipline in their camps and unwearied cultivation of the other arts of war. Without these, what chance would the inconsiderable numbers of the Roman armies have had against the multitudes of the Gauls? Or with what success would their small size have been opposed to the prodigious stature of the Germans? The Spaniards surpassed us not only in numbers, but in physical strength. We were always inferior to the Africans in wealth and unequal to them in deception and stratagem. And the Greeks, indisputably, were far superior to us in skill in arts and all kinds of knowledge. (Book 1)

Lu Xun studied medicine before he became a writer. Once he saw on a film a Chinese being executed by Japanese while many other Chinese were watching this "spectacular event". This made him feel that saving the "souls" of people is more important than saving their bodies.
Source: From the preface of his work Na Han (Call to Arms) (1922)

Jeff Bezos explains why Amazon doesn’t really care about its competitors http://www.geekwire.com/2013/interview-jeff-bezos-explains-amazon-focus-competitors/ 17 September, 2013.

Source: Enigmas Of Chance (1985), Chapter 4, On Toast!, p. 85.

"The Fundamental Idea of Wave Mechanics", Nobel lecture, (12 December 1933)
Context: Conditions are admittedly such that we can always manage to make do in each concrete individual case without the two different aspects leading to different expectations as to the result of certain experiments. We cannot, however, manage to make do with such old, familiar, and seemingly indispensable terms as "real" or "only possible"; we are never in a position to say what really is or what really happens, but we can only say what will be observed in any concrete individual case. Will we have to be permanently satisfied with this...? On principle, yes. On principle, there is nothing new in the postulate that in the end exact science should aim at nothing more than the description of what can really be observed. The question is only whether from now on we shall have to refrain from tying description to a clear hypothesis about the real nature of the world. There are many who wish to pronounce such abdication even today. But I believe that this means making things a little too easy for oneself.
Source: The Boy Book: A Study of Habits and Behaviors, Plus Techniques for Taming Them