“This [experimentation] is the custom—and properly so—in those sciences where mathematical demonstrations are applied to natural phenomena, as is seen in the case of perspective, astronomy, mechanics, music, and others where the principles, once established by well-chosen experiments, become the foundations of the entire superstructure.”

— Galileo Galilei

Salviati, Third Day. Change of Position
Dialogues and Mathematical Demonstrations Concerning Two New Sciences (1638)

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Galileo Galilei 70

Italian mathematician, physicist, philosopher and astronomer 1564–1642

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“[The mathematical character of Descartes' physics lies in its methodological nature, namely, the] axiomatic structure of the whole system, in the establishment of indubitable foundations and the deduction of the phenomena.”

Eduard Jan Dijksterhuis (1892–1965) Dutch historian

Source: The mechanization of the world picture, 1961, p. 414; as cited in: ‎Marleen Rozemond (2009), Descartes's Dualism. p. 235

“Experimenters are the shocktroops of science… An experiment is a question which science poses to Nature, and a measurement is the recording of Nature’s answer. But before an experiment can be performed, it must be planned – the question to nature must be formulated before being posed. Before the result of a measurement can be used, it must be interpreted – Nature’s answer must be understood properly. These two tasks are those of theorists, who find himself always more and more dependent on the tools of abstract mathematics.”

Max Planck (1858–1947) German theoretical physicist

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“There are, in fact, as I began to say above, not a few principles which are the special property of mathematics, such principles as are discovered by the common light of nature, require no demonstration, and which concern quantities primarily; then they are applied to other things, so far as the latter have something in common with quantities. Now there are more of these principles in mathematics than in the other theoretical sciences because of that very characteristic of the human understanding which seems to be such from the law of creation, that nothing can be known completely except quantities or by quantities. And so it happens that the conclusions of mathematics are most certain and indubitable.”

Johannes Kepler (1571–1630) German mathematician, astronomer and astrologer

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“Science does not speak of the world in the language of words alone, and in many cases it simply cannot do so. The natural language of science is a synergistic integration of words, diagrams, pictures, graphs, maps, equations, tables, charts, and other forms of visual and mathematical expression… [Science thus consists of] the languages of visual representation, the languages of mathematical symbolism, and the languages of experimental operations.”

Jay Lemke (1946) American academic

Jay Lemke (2003), "Teaching all the languages of science: Words , symbols, images and actions," p. 3; as cited in: Scott, Phil, Hilary Asoko, and John Leach. "Student conceptions and conceptual learning in science." Handbook of research on science education (2007): 31-56.

“The organic unity of mathematics is inherent in the nature of this science, for mathematics is the foundation of all exact knowledge of natural phenomena. That it may completely fulfil this high mission, may the new century bring it gifted masters and many zealous and enthusiastic disciples!”

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Mathematical Problems (1900)

“One finds in this subject a kind of demonstration which does not carry with it so high a degree of certainty as that employed in geometry; and which differs distinctly from the method employed by geometers in that they prove their propositions by well-established and incontrovertible principles, while here principles are tested by inferences which are derivable from them. The nature of the subject permits of no other treatment. It is possible, however, in this way to establish a probability which is little short of certainty. This is the case when the consequences of the assumed principles are in perfect accord with the observed phenomena, and especially when these verifications are numerous; but above all when one employs the hypothesis to predict new phenomena and finds his expectations realized.”

Christiaan Huygens book Treatise on Light

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“He has made contributions to many areas of science; among them are agronomy, anthropology, astronomy, bacteriology, botany, economics, forestry, meteorology, psychology, public health, and-above all-genetics, in which he is recognized as one of the leaders. Out of this varied scientific research and his skill in mathematics, he has evolved systematic principles for the interpretation of empirical data; and he has founded a science of experimental design. On the foundations he has laid down, there has been erected a structure of statistical techniques that are used whenever people attempt to learn about nature from experiment and observation.”

Ronald Fisher (1890–1962) English statistician, evolutionary biologist, geneticist, and eugenicist

W. Allen Wallis (1952) at the University of Chicago while honoring Fisher with the Honorary degree of Doctor of Science; cited in: George E. P. Box (1976) " Science and Statistics http://www-sop.inria.fr/members/Ian.Jermyn/philosophy/writings/Boxonmaths.pdf" Journal of the American Statistical Association, Vol. 71, No. 356. (Dec., 1976), pp. 791-799.

“Among all the studies of natural causes and reasons Light chiefly delights the beholder; and among the great features of Mathematics the certainty of its demonstrations is what preeminently (tends to) elevate the mind of the investigator. Perspective, therefore, must be preferred to all the discourses and systems of human learning. In this branch [of science] the beam of light is explained on those methods of demonstration which form the glory not so much of Mathematics as of Physics and are graced with the flowers of both.”

Leonardo Da Vinci (1452–1519) Italian Renaissance polymath

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“Our design, not respecting arts, but philosophy, and our subject, not manual, but natural powers, we consider chiefly those things which relate to gravity, levity, elastic force, the resistance of fluids, and the like forces, whether attractive or impulsive; and therefore we offer this work as mathematical principles of philosophy; for all the difficulty of philosophy seems to consist in this — from the phenomena of motions to investigate the forces of nature, and then from these forces to demonstrate the other phenomena…”

Isaac Newton book Philosophiae Naturalis Principia Mathematica

Preface
Philosophiae Naturalis Principia Mathematica (1687)

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Galileo Galilei 70

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