“The natural history of these islands is eminently curious, and well deserves attention. Most of the organic productions are aboriginal creations, found nowhere else; there is even a difference between the inhabitants of the different islands; yet all show a marked relationship with those of America, though separated from that continent by an open space of ocean, between 500 and 600 miles in width. The archipelago is a little world within itself, or rather a satellite attached to America, whence it has derived a few stray colonists, and has received the general character of its indigenous productions. Considering the small size of these islands, we feel the more astonished at the number of their aboriginal beings, and at their confined range. Seeing every height crowned with its crater, and the boundaries of most of the lava-streams still distinct, we are led to believe that within a period, geologically recent, the unbroken ocean was here spread out. Hence, both in space and time, we seem to be brought somewhat near to that great fact — that mystery of mysteries — the first appearance of new beings on this earth.”

Source: The Voyage of the Beagle (1839), chapter XVII: "Galapagos Archipelago" (second edition, 1845), entry for 8 October 1835, pages 377-378 http://darwin-online.org.uk/content/frameset?pageseq=390&itemID=F14&viewtype=image