“These days, my answer is if it's really primarily of interest to a very cosmopolitan philanthropist trying to help the whole future, and there's no one client and it's not frontier advancing, then I think that does make it pretty plausible to me that there's no one doing it.”

In an interview https://80000hours.org/podcast/episodes/holden-karnofsky-open-philanthropy/ with Robert Wiblin, February 2018; also quoted by Ben Pace in "Extended Quote on the Institution of Academia" https://www.lesswrong.com/posts/nXZi8efFArfk3u568/extended-quote-on-the-institution-of-academia and by Rob Bensinger in "Karnofsky on forecasting and what science does" https://www.lesswrong.com/posts/FhmWKE77qCPWJ63Y5/karnofsky-on-forecasting-and-what-science-does
Context: I think it's somewhat of a happy coincidence so far that most breakthroughs have been good. To say, I see a breakthrough on the horizon. Is that good or bad? How can we prepare for it? That's another thing academia is really not set up to do. Academia is set up to get the breakthrough. That is a question I ask myself a lot is here's an intellectual activity. Why can't it be done in academia? These days, my answer is if it's really primarily of interest to a very cosmopolitan philanthropist trying to help the whole future, and there's no one client and it's not frontier advancing, then I think that does make it pretty plausible to me that there's no one doing it. We would love to change that, at least somewhat, by funding what we think is the most important work.

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Holden Karnofsky 13
American nonprofit executive 1981

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