“It is courage based on confidence, not daring, and it is confidence based on experience.”
On testing his vaccine against polio on himself, his wife, and his three sons (9 May 1955)
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Jonas Salk 47
Inventor of polio vaccine 1914–1995Related quotes

Source: You Learn by Living (1960), p. 29–30
Context: You gain strength, courage and confidence by every experience in which you really stop to look fear in the face. You are able to say to yourself, "I have lived through this horror. I can take the next thing that comes along." … You must do the thing you think you cannot do.

“My message to you all is of hope, courage and confidence.”
Eid-ul-Azha Message to the Nation (24 October 1947)
Context: My message to you all is of hope, courage and confidence. Let us mobilize all our resources in a systematic and organized way and tackle the grave issues that confront us with grim determination and discipline worthy of a great nation.

“My theory is that all of Scottish cuisine is based on a dare.”
Elements of Style (1959).

Day of Affirmation Address (1966)
Context: The second danger is that of expediency: of those who say that hopes and beliefs must bend before immediate necessities. Of course, if we must act effectively we must deal with the world as it is. We must get things done. But if there was one thing that President Kennedy stood for that touched the most profound feeling of young people around the world, it was the belief that idealism, high aspirations, and deep convictions are not incompatible with the most practical and efficient of programs — that there is no basic inconsistency between ideals and realistic possibilities, no separation between the deepest desires of heart and of mind and the rational application of human effort to human problems. It is not realistic or hardheaded to solve problems and take action unguided by ultimate moral aims and values, although we all know some who claim that it is so. In my judgment, it is thoughtless folly. For it ignores the realities of human faith and of passion and of belief — forces ultimately more powerful than all of the calculations of our economists or of our generals. Of course to adhere to standards, to idealism, to vision in the face of immediate dangers takes great courage and takes self-confidence. But we also know that only those who dare to fail greatly, can ever achieve greatly.