“There are few states, I suppose, which exact so severe a toll from one's nervous system as the anticipation of calamity.”

Letter to his son http://radgeek.com/gt/2005/01/03/robert-e-Lee-owned-slaves-and-defended-slavery/, G. W. Custis Lee (23 January 1861).
1860s
Context: I can anticipate no greater calamity for the country than a dissolution of the Union. It would be an accumulation of all the evils we complain of, and I am willing to sacrifice everything but honor for its preservation. I hope, therefore, that all constitutional means will be exhausted before there is a resort to force. Secession is nothing but revolution. The framers of our Constitution never exhausted so much labor, wisdom, and forbearance in its formation, and surrounded it with so many guards and securities, if it was intended to be broken by every member of the Confederacy at will. It is intended for 'perpetual Union,' so expressed in the preamble, and for the establishment of a government, not a compact, which can only be dissolved by revolution, or the consent of all the people in convention assembled. It is idle to talk of secession: anarchy would have been established, and not a government, by Washington, Hamilton, Jefferson, Madison, and all the other patriots of the Revolution. … Still, a Union that can only be maintained by swords and bayonets, and in which strife and civil war are to take the place of brotherly love and kindness, has no charm for me. I shall mourn for my country and for the welfare and progress of mankind. If the Union is dissolved and the Government disrupted, I shall return to my native State and share the miseries of my people, and, save in defense will draw my sword on none.