“I can see no practical application of molecular biology to human affairs… DNA is a tangled mass of linear molecules in which the informational content is quite inaccessible.”

— Frank Macfarlane Burnet

Burnet, F.M. (1970) Immunological Surveillance. Pergamon Press. pp. 240-241.

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Frank Macfarlane Burnet 3

Australian virologist 1899–1985

Brian Swimme (1950) American cosmologist

From Journey of the Universe:

“In the next five years, molecular Darwinism—the idea that Darwinian processes can produce complex molecular structures at the subcellular level—will be dead. When that happens, evolutionary biology will experience a crisis of confidence because evolutionary biology hinges on the evolution of the right molecules. I therefore foresee a Taliban-style collapse of Darwinism in the next ten years. Intelligent design will of course profit greatly from this.”

William A. Dembski (1960) American intelligent design advocate

" Measure of Design: A Conversation About the Past, Present & Future of Darwinism & Design http://www.touchstonemag.com/archives/article.php?id=17-06-060-i#ixzz2elFILC9O|The" Touchstone, volume 17, issue 6, pages 60-65, at page 64 (July/August 2004).
2000s

“Both of us had decided, quite independently of each other, that the central problem in molecular biology was the chemical structure of the gene.”

Francis Crick (1916–2004) British molecular biologist, biophysicist, neuroscientist; co-discoverer of the structure of DNA

What Mad Pursuit (1988)

“It is easy to think of DNA as the information by which a body makes another body like itself. It would be more correct to see a body as the vehicle used by DNA to make more DNA like itself.”

Richard Dawkins book Climbing Mount Improbable

Source: Climbing Mount Improbable (1996), Chapter 3, “The Message from the Mountain” (pp. 89-90)

“We may, I believe, anticipate that the chemist of the future who is interested in the structure of proteins, nucleic acids, polysaccharides, and other complex substances with high molecular weight will come to rely upon a new structural chemistry, involving precise geometrical relationships among the atoms in the molecules and the rigorous application of the new structural principles, and that great progress will be made, through this technique, in the attack, by chemical methods, on the problems of biology and medicine.”

Linus Pauling (1901–1994) American scientist

Nobel Lecture (11 December 1954).
1940s-1960s

“The shapes of molecules influence their behavior and function, especially the ease with which they can fit into various guest-host configurations important in biology and biochemistry.”

David W. Oxtoby (1951) President of Pomona college

Principles of Modern Chemistry (7th ed., 2012), Ch. 3 : Classical Bonding: The Classical Description

“Indeed, many of the founding members of the Laboratory of Molecular Biology were immigrants themselves, and they helped to revolutionise modern biology.”

Venkatraman Ramakrishnan (1952) Nobel prize winning American and British structural biologist

Quoted in "Knighthood for Venkatraman Ramakrishnan".

“The entire recent history of biology shows that we are, to a remarkable degree, the results of the interactions of an extremely complex array of molecules; and the aspect of biology that was once considered its holy of holies, the nature of the genetic material, has now been fundamentally understood in terms of the chemistry of its constituent nucleic acids, DNA and RNA, and their operational agents, the proteins.”

Carl Sagan (1934–1996) American astrophysicist, cosmologist, author and science educator

Introduction (p. 7)
The Dragons of Eden (1977)

“With each new discovery of chemistry, physics, biology, the anthropological sciences, of the practical application of sound principles, dogma collapses. It is a part of that old edifice of religion which crumbles and falls in ruins.”

Benito Mussolini (1883–1945) Duce and President of the Council of Ministers of Italy. Leader of the National Fascist Party and subsequen…

1900s, God Does Not Exist (1904)

“While it was long possible and sometimes tempting for physicists to deny the usefulness of the molecular hypothesis, we economists have the good luck of being some of the ‘molecules’ of economic life ourselves, and of having the possibility through human contacts to study the behavior of other ‘molecules’.”

Tjalling Koopmans (1910–1985) Dutch American economist

Tjalling Koopmans in: Review of economics and statistics, Vol. 31 -(1949), p. 87

“I can see no practical application of molecular biology to human affairs… DNA is a tangled mass of linear molecules in which the informational content is quite inaccessible.”

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Frank Macfarlane Burnet 3

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