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“It should not for a moment be supposed that cultivation of the intellect leads a man to shrink from inflicting pain. Many educated men are no more humane, are in fact far less so, than many comparatively uneducated people.”

Henry Jacob Bigelow (1818–1890) American surgeon

Source: Surgical Anaesthesia (1894), p. 365

“My experience is that everything is bliss. But the desire for bliss creates pain. Thus bliss becomes the seed of pain. The entire universe of pain is born of desire. Give up the desire for pleasure and you will not even know what is pain. (…) for the sake of pleasure you are committing many sins. And the fruits of sin are suffering and death.”

Nisargadatta Maharaj (1897–1981) Indian guru

Desire and fear
Source: "I am That." P.82.

“Pleasure is never as pleasant as we expected it to be and pain is always more painful. The pain in the world always outweighs the pleasure. If you don't believe it, compare the respective feelings of two animals, one of which is eating the other.”

Arthur Schopenhauer (1788–1860) German philosopher

“The trick is not how much pain you feel--but how much joy you feel. Any idiot can feel pain. Life is full of excuses to feel pain, excuses not to live, excuses, excuses, excuses.”

Erica Jong (1942) Novelist, poet, memoirist, critic

“Make no mistake about it, making a good record is pure, unadulterated pain. If you fall and break your leg--that's pain. But I'm telling you, the phase between pain and death? That's making a good record. It's extreme.”

Ben Harper (1969) singer-songwriter and musician

Roots Radical http://www.highbeam.com/doc/1G1-57534351.html, Guitar Player (December 1, 1999).

“Every pain is a lesson.”

Frank Delaney (1942–2017) Irish writer and journalist

Source: The Matchmaker of Kenmare

“In the face of pain there are no heroes.”

George Orwell book 1984

Source: 1984

“Take pains. Be perfect.”

William Shakespeare A Midsummer Night's Dream

Source: A Midsummer Night's Dream

“There's no love without pain.”

Irving Stone book Lust for Life

Source: Lust for Life

“Pain was a fascinating horror”

Aldous Huxley book Brave New World

Source: Brave New World

“The purpose exceeds the pain.”

Beth Moore (1957) American evangelist

“A joy as intense as pain”

Nicholas Sparks (1965) American writer and novelist

“All pain is the same.”

Oprah Winfrey (1954) American businesswoman, talk show host, actress, producer, and philanthropist

“Remorse is the pain of sin.”

Theodore Parker (1810–1860) abolitionist

As quoted in Man a revelation of God (1888) by George Everett Ackerman, p. 254.

“Pain is never permanent.”

Teresa of Ávila (1515–1582) Roman Catholic saint

The Book of Positive Quotations (2007) edited by John Cook, Steve Deger, and Leslie Ann Gibson, p. 333

“Labour for his pains.”

Edward Moore (1712–1757) English dramatist and writer

The Boy and the Rainbow. Compare: "I have had my labour for my travail", William Shakespeare, Troilus and Cressida, Act i., Sc. 1.
Bartlett's Familiar Quotations, 10th ed. (1919)

“Pain is the kiss of Christ.”

Catherine Doherty (1896–1985) Religious order founder; Servant of God

Dearly Beloved, Vol. III (1990)

“The contest will continue — the contest between those who see a monolithic world and those who believe in diversity — but it should be a contest in leadership and responsibility instead of destruction, a contest in achievement instead of intimidation. Speaking for the United States of America, I welcome such a contest. For we believe that truth is stronger than error — and that freedom is more enduring than coercion. And in the contest for a better life, all the world can be a winner.”

John F. Kennedy (1917–1963) 35th president of the United States of America

1963, UN speech

“Science has taught… me to be careful how I adopt a view which jumps with my preconceptions, and to require stronger evidence for such belief than for one to which I was previously hostile. My business is to teach my aspirations to conform themselves to fact, not to try and make facts harmonise with my aspirations.”

Thomas Henry Huxley (1825–1895) English biologist and comparative anatomist

1860s, Reply to Charles Kingsley (1860)

“Pain and suffering, they are a secret. Kindness and love, they are a secret. But I have learned that kindness and love can pay for pain and suffering.”

Alan Paton (1903–1988) South African writer and activist

Source: Cry, The Beloved Country