Sir Isaac Newton was an English mathematician, astronomer, and physicist who is widely recognised as one of the most influential scientists of all time and a key figure in the scientific revolution. His book Philosophiæ Naturalis Principia Mathematica , first published in 1687, laid the foundations of classical mechanics. Newton also made pathbreaking contributions to optics, and he shares credit with Gottfried Wilhelm Leibniz for developing the infinitesimal calculus.

Newton's Principia formulated the laws of motion and universal gravitation that dominated scientists' view of the physical universe for the next three centuries. By deriving Kepler's laws of planetary motion from his mathematical description of gravity, and using the same principles to account for the trajectories of comets, the tides, the precession of the equinoxes, and other phenomena, Newton removed the last doubts about the validity of the heliocentric model of the Solar System and demonstrated that the motion of objects on Earth and of celestial bodies could be accounted for by the same principles. Newton's theoretical prediction that the Earth is shaped as an oblate spheroid was later vindicated by the geodetic measurements of Maupertuis, La Condamine, and others, thus convincing most Continental European scientists of the superiority of Newtonian mechanics over the earlier system of Descartes.

Newton also built the first practical reflecting telescope and developed a sophisticated theory of colour based on the observation that a prism decomposes white light into the colours of the visible spectrum. Newton's work on light was collected in his highly influential book Opticks, first published in 1704. He also formulated an empirical law of cooling, made the first theoretical calculation of the speed of sound, and introduced the notion of a Newtonian fluid. In addition to his work on calculus, as a mathematician Newton contributed to the study of power series, generalised the binomial theorem to non-integer exponents, developed a method for approximating the roots of a function, and classified most of the cubic plane curves.

Newton was a fellow of Trinity College and the second Lucasian Professor of Mathematics at the University of Cambridge. He was a devout but unorthodox Christian, who privately rejected the doctrine of the Trinity and who, unusually for a member of the Cambridge faculty of the day, refused to take holy orders in the Church of England. Beyond his work on the mathematical sciences, Newton dedicated much of his time to the study of alchemy and biblical chronology, but most of his work in those areas remained unpublished until long after his death. Politically and personally tied to the Whig party, Newton served two brief terms as Member of Parliament for the University of Cambridge, in 1689–90 and 1701–02. He was knighted by Queen Anne in 1705 and he spent the last three decades of his life in London, serving as Warden and Master of the Royal Mint, as well as president of the Royal Society .